典型文献
Development of stable,cold-adapted,temperature-sensitive/conditional lethal chimeric enterovirus A71 and coxsackievirus A16
文献摘要：
Dear Editor,
Coxsackievirus A16(CA16)and enterovirus A71(EV-A71)are the main causative agents of hand foot and mouth disease(HFMD)(Alex-ander et al.,1994).Besides HFMD,EV-A71 infection in young children can lead to a spectrum of other clinical diseases and associated neuro-logical complications and mortality(Melnick JL.,1996).In recent de-cades,EV-A71 infections have become a major public health concern throughout the world,following the frequent occurrence of epidemics and outbreaks of HFMD associated with neurological complications and high mortality in young children(Ishimaru et al.,1980;Tagaya et al.,1981;Chomnaitree et al.,1982;Samuda et al.,1987;Gilbert et al.,1988;Hayward et al.,1989;Lum et al.,1998;Chang et al.,1998;Liu et al.,2000;Yang et al.,2011;Zeng et al.,2012).
文献关键词：
中图分类号：
作者姓名：
Kaw Bing Chua;Qimei Ng;Tao Meng;Qiang Jia
作者机构：
Temasek Life Sciences Laboratory,1 Research Link,National University of Singapore,117604,Singapore
文献出处：
引用格式：
[1]Kaw Bing Chua;Qimei Ng;Tao Meng;Qiang Jia-.Development of stable,cold-adapted,temperature-sensitive/conditional lethal chimeric enterovirus A71 and coxsackievirus A16)[J].中国病毒学,2022(05):769-773
A类：
Coxsackievirus,ander,Melnick,Ishimaru,Tagaya,Chomnaitree,Samuda,Lum
B类：
Development,stable,cold,adapted,temperature,sensitive,conditional,lethal,chimeric,enterovirus,A71,coxsackievirus,Dear,Editor,CA16,EV,are,main,causative,agents,hand,foot,mouth,HFMD,Alex,Besides,young,children,can,lead,spectrum,other,clinical,diseases,associated,complications,mortality,JL,In,recent,cades,infections,have,become,major,public,health,concern,throughout,world,following,frequent,occurrence,epidemics,outbreaks,neurological,high,Gilbert,Hayward,Chang,Liu,Yang,Zeng
AB值：
0.503227
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