典型文献
A BAF-fling connection to RIPK1
文献摘要：
RIPK1 is a multifaceted kinase with roles in diverse cellular processes,including cell death,innate immunity,and inflam-matory signaling.RIPK1 can also facilitate inflammatory diseases,like amyotrophic lateral sclerosis(ALS)and Alzhei-mer's disease(AD),independent of its cell death functions;in a recent Cell Research paper,Li et al.show that this results from RIPK1 acting as a transcriptional coregulator,forming a nuclear complex with the BAF complex through direct interactions with BRG1 and SMARCC2,mediating phosphor-ylation of SMARCC2,and promoting chromatin remodeling and transcription of proinflammatory genes.
文献关键词：
中图分类号：
作者姓名：
Jessica M.Gullett;Thirumala-Devi Kanneganti
作者机构：
Department of Immunology,St.Jude Children's Research Hospital,Memphis,TN,USA
文献出处：
引用格式：
[1]Jessica M.Gullett;Thirumala-Devi Kanneganti-.A BAF-fling connection to RIPK1)[J].细胞研究（英文版）,2022(08):709-710
A类：
fling,coregulator,SMARCC2
B类：
BAF,connection,RIPK1,multifaceted,kinase,roles,diverse,cellular,processes,including,death,innate,immunity,signaling,can,also,facilitate,diseases,like,amyotrophic,lateral,sclerosis,ALS,Alzhei,mer,AD,independent,its,functions,recent,Cell,Research,paper,Li,show,that,this,results,from,acting,transcriptional,forming,nuclear,complex,through,direct,interactions,BRG1,mediating,phosphor,ylation,promoting,chromatin,remodeling,proinflammatory,genes
AB值：
0.64586
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
