典型文献
Progress in DNA Aptamers as Recognition Components for Protein Functional Regulation
文献摘要:
Proteins play a central role in all domains of life,and precise regulation of their activity is essential for understanding the related biological processes and therapeutic functions.Nucleic acid aptamers,the molecular recognition components derived from systematic evolution of ligands by exponential enrichment(SELEX),can specifically identify proteins with antibody-like recognition characteristics and help to regulate their activity.This minireview covers the SELEX-based selection of protein-binding aptamers,membrane protein analytical techniques based on aptamer-mediated target recognition,aptamer-mediated functional regulation of proteins,including membrane receptors and non-membrane proteins(thrombin as a model),as well as the potential challenges and prospects regarding aptamer-mediated protein manipulation,aiming to supply some useful information for researchers in this field.
文献关键词:
中图分类号:
作者姓名:
HU Lingling;LIU Ke;REN Guolan;LIANG Jiangong;WU Yuan
作者机构:
College of Science,Huazhong Agricultural University,Wuhan 430070,P.R China
文献出处:
引用格式:
[1]HU Lingling;LIU Ke;REN Guolan;LIANG Jiangong;WU Yuan-.Progress in DNA Aptamers as Recognition Components for Protein Functional Regulation)[J].高等学校化学研究(英文版),2022(04):894-901
A类:
Aptamers
B类:
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AB值:
0.64629
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