首站-论文投稿智能助手
典型文献
Progress in DNA Aptamers as Recognition Components for Protein Functional Regulation
文献摘要:
Proteins play a central role in all domains of life,and precise regulation of their activity is essential for understanding the related biological processes and therapeutic functions.Nucleic acid aptamers,the molecular recognition components derived from systematic evolution of ligands by exponential enrichment(SELEX),can specifically identify proteins with antibody-like recognition characteristics and help to regulate their activity.This minireview covers the SELEX-based selection of protein-binding aptamers,membrane protein analytical techniques based on aptamer-mediated target recognition,aptamer-mediated functional regulation of proteins,including membrane receptors and non-membrane proteins(thrombin as a model),as well as the potential challenges and prospects regarding aptamer-mediated protein manipulation,aiming to supply some useful information for researchers in this field.
文献关键词:
作者姓名:
HU Lingling;LIU Ke;REN Guolan;LIANG Jiangong;WU Yuan
作者机构:
College of Science,Huazhong Agricultural University,Wuhan 430070,P.R China
引用格式:
[1]HU Lingling;LIU Ke;REN Guolan;LIANG Jiangong;WU Yuan-.Progress in DNA Aptamers as Recognition Components for Protein Functional Regulation)[J].高等学校化学研究(英文版),2022(04):894-901
A类:
Aptamers
B类:
Progress,Recognition,Components,Functional,Regulation,Proteins,play,central,role,domains,life,precise,regulation,their,activity,essential,understanding,related,biological,processes,therapeutic,functions,Nucleic,acid,aptamers,molecular,recognition,components,derived,from,systematic,evolution,ligands,by,exponential,enrichment,SELEX,can,specifically,identify,proteins,antibody,like,characteristics,help,regulate,This,minireview,covers,selection,binding,membrane,analytical,techniques,mediated,target,functional,including,receptors,thrombin,model,well,potential,challenges,prospects,regarding,manipulation,aiming,supply,some,useful,information,researchers,this,field
AB值:
0.64629
相似文献
Bioinspired Self-assembly Nanochaperone Inhibits Tau-Derived PHF6 Peptide Aggregation in Alzheimer's Disease
Lin Zhu;Ming-Qing Zhang;Hao-Ren Jing;Xi-Peng Zhang;Lin-Lin Xu;Ru-Jiang Ma;Fan Huang;Lin-Qi Shi-State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Functional Polymer Materials of Ministry of Education,College of Chemistry,Nankai University,Tianjin 300071,China;Nankai University School of Medicine,Nankai University,Tianjin,China Department of Colorectal Surgery,Tianjin Union Medical Center,Tianjin 300074,China;Department of Colorectal Surgery,Tianjin Union Medical Center,Tianjin 300121,China;Key Laboratory of Radiopharmacokinetics for Innovative Drugs,Chinese Academy of Medical Sciences,and Institute of Radiation Medicine,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300192,China
Multi-Omics Analysis Provides Insight into the Possible Molecular Mechanism of Hay Fever Based on Gut Microbiota
Pei Han;Li-Sha Li;Zi-Xi Wang;Lin Xi;Hang Yu;Lin Cong;Zheng-Wei Zhang;Jie Fu;Ran Peng;Li-Bin Pan;Shu-Rong Ma;Xue-Yan Wang;Hong-Tian Wang;Xiang-Dong Wang;Yan Wang;Jin-Lyu Sun;Jian-Dong Jiang-State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100050,China;Department of Allergy,National Clinical Research Center for Dematologic and Immunologic Diseases,Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Allergy&Department of Otorhinolaryngology Head and Neck Surgery&Key Laboratory of Otolaryngology Head and Neck Surgery,Ministry of Education,Beijing Tongren Hospital,Capital Medical University,Beijing 100005,China;Department of Allergy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;Beijing Key Laboratory of Nasal Diseases,Beijing Institute of Otolaryngology,Beijing Tongren Hospital,Capital Medical University,Beijing 100005,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。