典型文献
Selected aptamer specially combing 5-8F cells based on automatic screening instrument
文献摘要：
Since the concept of aptamer emerged,many scientists have launched a rich field of research around it.However,few nucleic acids aptamer which use cell as target can be put into practical applications.We believe that a great deal of this lies in the complexity and irreproducibility of aptamer screening exper-iments themselves.The complexity is due to the cumbersome processes and the technical requirements for laboratory personnel,whereas irreproducibility arises from the fact that the starting point of such screens is nucleic acid libraries with random fragments,and that different libraries directly determine the differences or even the success or failure of screening results.The complexity and irreproducibility mentioned above,in turn,lead to the inability of this experiment to unfold on a large scale,which natu-rally cannot lead to excellent results for practical applications.In response to this problem,our group has developed an instrument for automated screening of tumor cell nucleic acid aptamers and characterized the properties of nucleic acid aptamers obtained using this instrument in a comprehensive manner.
文献关键词：
中图分类号：
作者姓名：
Zhukang Guo;Baijiang Jin;Yile Fang;Yan Deng;Zhu Chen;Hui Chen;Song Li;Franklin Wang-Ngan Chow;Polly H.M.Leung;Hanming Wang;Lei Cai;Nongyue He
作者机构：
State Key Laboratory of Bioelectronics,School of Biological Science and Medical Engineering,Southeast University,Nanjing 210096,China;Hunan Key Laboratory of Biomedical Nanomaterials and Devices,Hunan University of Technology,Zhuzhou 412007,China;Department of Health Technology and Informatics,The Hong Kong Polytechnic University,Hong Kong,China;Guangzhou Wondfo Biotech Co.,Ltd.,Guangzhou 510641,China;Guangzhou Wondfo iCubate Biotech Co.,Ltd.,Guangzhou 510641,China
文献出处：
引用格式：
[1]Zhukang Guo;Baijiang Jin;Yile Fang;Yan Deng;Zhu Chen;Hui Chen;Song Li;Franklin Wang-Ngan Chow;Polly H.M.Leung;Hanming Wang;Lei Cai;Nongyue He-.Selected aptamer specially combing 5-8F cells based on automatic screening instrument)[J].中国化学快报（英文版）,2022(09):4208-4212
A类：
irreproducibility
B类：
Selected,specially,combing,8F,cells,automatic,screening,instrument,Since,concept,emerged,many,scientists,have,launched,rich,field,research,around,However,few,nucleic,acids,which,use,target,put,into,practical,applications,We,believe,that,great,deal,this,lies,complexity,iments,themselves,due,cumbersome,processes,technical,requirements,laboratory,personnel,whereas,arises,from,fact,starting,point,such,screens,libraries,random,fragments,different,directly,determine,differences,even,success,failure,results,mentioned,above,turn,lead,inability,experiment,unfold,large,scale,natu,rally,cannot,excellent,In,response,problem,our,group,has,developed,automated,tumor,aptamers,characterized,properties,obtained,using,comprehensive,manner
AB值：
0.599532
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
