典型文献
Iron manganese silicate incorporated bioactive hydrogels for therapy of skin tumor
文献摘要:
There is clinical need to develop a multifunctional composite hydrogel for effectively removing residual tumor tissue and promoting wound healing after surgical resection of skin tumors.Herein,an iron manganese silicate(FeMn(SiO4))-incorporated bioactive hydrogel for photothermal therapy of skin tumor cells has been successfully designed in the present study.The synthesized FeMn(SiO4)(FMS)possessed a hollow sphere structure with rough surface,showing favorable photothermal effect.By incorporating FMS into the sodium alginate(SA)hydrogel,the prepared composite hydrogel(FMS/SA)exhibited the function of eliminating skin tumor cells in vitro by pho-tothermal therapy(PTT).Moreover,attributed to the released bioactive ions(e.g..,Fe,Mn and Si ions)from FMS,the FMS/SA composite hydrogel presented desirable biocompatibility,which is expected to benefit for skin wound healing of patients after skin tumor resection.Overall,the FMS/SA composite hydrogel has potential application in skin tumor therapy and wound healing,providing an effective and feasible strategy for the development of a comprehensive therapy for skin tumor after surgery.
文献关键词:
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作者姓名:
Wenping Ma;Hongjian Zhang;Hongshi Ma;Chengtie Wu
作者机构:
State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai,200050,China;Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,19 Yuquan Road,Beijing 100049,China
文献出处:
引用格式:
[1]Wenping Ma;Hongjian Zhang;Hongshi Ma;Chengtie Wu-.Iron manganese silicate incorporated bioactive hydrogels for therapy of skin tumor)[J].自然科学进展·国际材料(英文),2022(02):171-178
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0.496535
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