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典型文献
In situ wound sprayable double-network hydrogel:Preparation and characterization
文献摘要:
In clinical settings the wound-dressing was required easy to use and can match the wound area immedi-ately,at the same time they need to have the properties of hemostats,anti-inflammation and promoting wound healing.To get an ideal wound dressing,we developed a type of gel-like wound adhesive patch from spraying double-network hydrogel,which own the properties of self-antibacterial and can promote wound healing.By spraying,the gel-like wound adhesive patch can match the wound area immediately and form a gel-film in 10 s.Sodium carboxymethyl cellulose as pH sensitive materials accelerated the speed to form the gel-film and enhanced ductility of the wound adhesive patch.In vitro experiments show that,this gel-like wound adhesive patch can promote cell proliferation and reduce cell apoptosis.In vivo studies show that,compared with commercialized wound dressings in clinic using,the spraying gel-like wound adhesive patch from our work has a better effect on wound healing.In conclusion,the spraying gel-like wound patch in our work is easy to use and can form a gel-film match on wound area in a short time,also it has the properties of hemostats,anti-inflammation and promoting wound healing.Its feasibility for mass production shows a good potential for commercial use.
文献关键词:
作者姓名:
Chenglong Cai;Ting Wang;Xu Han;Shaoqiang Yang;Chengteng Lai;Tao Yuan;Zhangqi Feng;Nongyue He
作者机构:
State Key Laboratory of Bioelectronics,National Demonstration Centre for Experimental Biomedical Engineering Education,School of Biological Science and Medical Engineering,Southeast University,Nanjing 210096,China;Southeast University Jiangbei New Area Innovation Institute,Nanjing 210096,China;Nanjing Jinling Hosp,Dept Orthoped,Nanjing 210002,China;School of Chemical Engineering,Nanjing University of Science and Technology,Nanjing 210094,China
引用格式:
[1]Chenglong Cai;Ting Wang;Xu Han;Shaoqiang Yang;Chengteng Lai;Tao Yuan;Zhangqi Feng;Nongyue He-.In situ wound sprayable double-network hydrogel:Preparation and characterization)[J].中国化学快报(英文版),2022(04):1963-1969
A类:
hemostats
B类:
In,situ,wound,sprayable,double,network,hydrogel,Preparation,characterization,clinical,settings,was,required,easy,use,can,match,area,same,they,need,have,properties,inflammation,promoting,healing,To,get,ideal,we,developed,type,like,adhesive,patch,from,spraying,which,own,self,antibacterial,promote,By,immediately,form,film,Sodium,carboxymethyl,cellulose,sensitive,materials,accelerated,speed,enhanced,ductility,vitro,experiments,that,this,proliferation,reduce,apoptosis,vivo,studies,compared,commercialized,dressings,using,our,has,better,effect,conclusion,short,also,Its,feasibility,mass,production,shows,good,potential
AB值:
0.40226
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