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典型文献
Polyhexamethylene biguanide chemically modified cotton with desirable hemostatic,inflammation-reducing,intrinsic antibacterial property for infected wound healing
文献摘要:
Medical cotton dressing is cheap and widely used in diversified fields,but in the application of promot-ing wound healing,the continuous research of multifunctional medical cotton dressing is still of great significance.Here,we developed a fresh type of antibacterial cotton dressing through a succinct strategy based on chemically anchoring polyhexamethylene biguanide(PHMB).Intriguingly,after PHMB modifica-tion,the cotton dressing exhibited outstanding antibacterial performance which could maintain>99.99%antibacterial rate after several treatments,including washing 50 times,repeated use 10 times,UV irradi-ation for 7 days,cationic dyes dying,and conditioned under 90℃water bath for 2 h.In addition,the water contact angle of cotton dressing increased dramatically from 0° to 111°,which could facilitate bac-terial adhesion,thus further enhance the antibacterial efficiency,and easily remove the bacterial debris.Apart from that,the developed cotton dressing showed good cytocompatibility,promoted blood clotting and expression of platelets,and promoted the wound healing process in the infection intervened skin wound model.Taken together,this antibacterial cotton dressing with desirable blood clotting,sustained protection against bacterial infection and bacterial removal features shows the potential to be a candidate for infected skin wound healing.
文献关键词:
作者姓名:
Chuan Guo;Jie Zhang;Xiaojun Feng;Zhenggui Du;Yuanzhang Jiang;Yidong Shi;Guanghui Yang;Lin Tan
作者机构:
College of Biomass Science and Engineering,Key Laboratory of Leather Chemistry and Engineering of Ministry of Education,Sichuan University,Chengdu 610065,China;Department of Breast Surgery,West China Hospital,Sichuan University,Chengdu 610041,China;School of Materials and Environmental Engineering,Shenzhen Polytechnic,Shenzhen 518000,China;State Key Laboratory of Polymer Materials Engineering,Sichuan University,Chengdu 610065,China
引用格式:
[1]Chuan Guo;Jie Zhang;Xiaojun Feng;Zhenggui Du;Yuanzhang Jiang;Yidong Shi;Guanghui Yang;Lin Tan-.Polyhexamethylene biguanide chemically modified cotton with desirable hemostatic,inflammation-reducing,intrinsic antibacterial property for infected wound healing)[J].中国化学快报(英文版),2022(06):2975-2981
A类:
Polyhexamethylene,biguanide,polyhexamethylene
B类:
chemically,modified,cotton,desirable,hemostatic,inflammation,reducing,intrinsic,antibacterial,property,infected,wound,healing,Medical,dressing,cheap,widely,used,diversified,fields,but,application,continuous,research,multifunctional,medical,still,great,significance,Here,developed,fresh,type,through,succinct,strategy,anchoring,PHMB,Intriguingly,after,modifica,exhibited,outstanding,performance,which,could,maintain,several,treatments,including,washing,times,repeated,UV,irradi,days,cationic,dyes,dying,conditioned,under,water,bath,addition,contact,angle,increased,dramatically,from,facilitate,adhesion,thus,further,enhance,efficiency,easily,remove,debris,Apart,that,showed,good,cytocompatibility,promoted,blood,clotting,expression,platelets,process,infection,intervened,skin,model,Taken,together,this,sustained,protection,against,removal,features,shows,potential,be,candidate
AB值:
0.55285
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