典型文献
Recombinant human interferon-α1b inhibits SARS-CoV-2 better than interferon-α2b in vitro
文献摘要:
Dear Editor,
The coronavirus disease 2019(COVID-19)outbreak,has spread across the world(Wu et al.,2020).The causative agent of COVID-19,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is highly pathogenic and infectious,which become a major public health hazard that has had a devastating social and economic impact worldwide(Li Q.Q.et al.,2020).
Variants of the virus have emerged that behave differently(CDC 2021;Gobeil et al.,2020;Leung et al.,2021).Some of them show increased infectivity(Li Q.et al.,2020;Zhang et al.,2020)and may escape from neutralizing antibodies(Weisblum et al.,2020).Various vaccines have been developed and marketed for COVID-19.However,there is a shortage of specific drugs to treat this novel virus and there is an urgent need for effective broad-spectrum anti-viral drugs to treat COVID-19 and its variants.
文献关键词:
中图分类号:
作者姓名:
Danrong Shi;Keda Chen;Xiangyun Lu;Linfang Cheng;Tianhao Weng;Fumin Liu;Nanping Wu;Lanjuan Li;Hangping Yao
作者机构:
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,National Medical Center for Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,310003,China;Shulan International Medical College,Zhejiang Shuren University,Hangzhou,310015,China
文献出处:
引用格式:
[1]Danrong Shi;Keda Chen;Xiangyun Lu;Linfang Cheng;Tianhao Weng;Fumin Liu;Nanping Wu;Lanjuan Li;Hangping Yao-.Recombinant human interferon-α1b inhibits SARS-CoV-2 better than interferon-α2b in vitro)[J].中国病毒学,2022(02):295-298
A类:
Variants,Gobeil,Leung,Weisblum
B类:
Recombinant,human,interferon,1b,inhibits,SARS,CoV,better,than,2b,vitro,Dear,Editor,
The,coronavirus,disease,outbreak,has,spread,across,Wu,causative,agent,severe,acute,respiratory,syndrome,highly,pathogenic,infectious,which,become,major,public,health,hazard,that,had,devastating,social,economic,impact,worldwide,Li,emerged,behave,differently,CDC,Some,them,show,increased,infectivity,Zhang,may,escape,from,neutralizing,antibodies,Various,vaccines,been,developed,marketed,However,there,shortage,specific,drugs,treat,this,novel,urgent,need,effective,broad,spectrum,viral,variants
AB值:
0.626835
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