典型文献
Internet of things(IoT)imbedded point-of-care SARS-CoV-2 testing in the pandemic and post-pandemic era
文献摘要：
The outbreaks of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron variant in China have revealed a high rate of asymptomatic cases,making isolation and quarantine measures exceedingly dif-ficult.Public health surveillance and intervention measures will require rapid and accurate testing preferably on-site using point-of-care tests(POCTs)technology for SARS-CoV-2 variants.However,delayed and/or inac-curate surveillance data is a major obstacle blocking the large-scale implementation of POCTs in curbing spread of infectious pathogens and reducing mortality during an outbreak.To determine levels of community trans-mission and timely strategies accordingly,highly sensitive and specific POCT embedded with the internet of things(IoT)technology could enable on-site screening and real-time data collection.A new Rapid Amplification with Sensitivity And Portability point-of-care test(RASAP-POCT)system based on thermal con-vection PCR is the first IoT-based isothermal nucleic acid amplification POCT,which can provide test results within 20-30 min using saliva and/or nasopharyngeal swab samples without nucleic acid extraction.With the IoT-imbedded feature,the RASAP-POCT system can be integrated easily and smoothly with China's existing mobile-phone-based contact tracing system,which has previously proved to be highly effective in maintaining the dynamic zero-COVID policy.Current regulatory guidelines and rules should be modified to accelerate the adoption of new technologies under an emergency use authorization(EUA).
文献关键词：
中图分类号：
作者姓名：
Zhaoxi Wang;Simin Liu
作者机构：
Beth Israel Deaconess Medical Center/Harvard Medical School,Boston,MA 02215,United States;Department of Epidemiology,Brown University,Providence,RI 02912,United States
文献出处：
引用格式：
[1]Zhaoxi Wang;Simin Liu-.Internet of things(IoT)imbedded point-of-care SARS-CoV-2 testing in the pandemic and post-pandemic era)[J].生物安全与健康 （英文）,2022(06):365-368
A类：
POCTs,Portability,RASAP
B类：
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AB值：
0.626176
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