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典型文献
Nanomagnet-facilitated pharmaco-compatibility for cancer diagnostics:Underlying risks and the emergence of ultrasmall nanomagnets
文献摘要:
Cancer therapy is a fast-emerging biomedical paradigm that elevates the diagnostic and therapeutic po-tential of a nanovector for identification,monitoring,targeting,and post-treatment response analysis.Nanovectors of superparamagnetic iron oxide nanoparticles(SPION)are of tremendous significance in cancer therapy because of their inherited high surface area,high reactivity,biocompatibility,superior contrast,and magnetic and photo-inducibility properties.In addition to a brief introduction,we summarize various progressive aspects of nanomagnets pertaining to their production with an emphasis on sustainable biomimetic approaches.Post-synthesis particulate and surface alterations in terms of pharmaco-affinity,liquid accessibility,and biocompatibility to facilitate cancer therapy are highlighted.SPION parameters including particle contrast,core-fusions,surface area,reactivity,photosensitivity,photodynamics,and photothermal properties,which facilitate diverse cancer diagnostics,are discussed.We also elaborate on the concept of magnetism to selectively focus chemotherapeutics on tumors,cell sorting,purification of bio-entities,and elimination of toxins.Finally,while addressing the toxicity of nanomaterials,the advent of ultrasmall nanomagnets as a healthier alternative with superior properties and compatible cellular in-teractions is reviewed.In summary,these discussions spotlight the versatility and integration of multi-tasking nanomagnets and ultrasmall nanomagnets for diverse cancer theragnostics.
文献关键词:
作者姓名:
Divya S.Parimi;Yamini Gupta;Sreekar Marpu;Chandra S.Bhatt;Tharun K.Bollu;Anil K.Suresh
作者机构:
Bionanotechnology&Sustainable Laboratory,Department of Biological Sciences,School of Engineering and Applied Sciences,Sri Ramaswamy Memorial(SRM)University,Amaravati,522503,India;Department of Chemistry,University of North Texas,Denton,TX,76201,USA;Department of Biotechnology,Faculty of Science and Humanities,Sri Ramaswamy Memorial(SRM)Institute of Science and Technology,Chennai,603203,India
引用格式:
[1]Divya S.Parimi;Yamini Gupta;Sreekar Marpu;Chandra S.Bhatt;Tharun K.Bollu;Anil K.Suresh-.Nanomagnet-facilitated pharmaco-compatibility for cancer diagnostics:Underlying risks and the emergence of ultrasmall nanomagnets)[J].药物分析学报(英文),2022(03):365-379
A类:
Nanomagnet,nanomagnets,nanovector,Nanovectors,inducibility,photodynamics,tasking,theragnostics
B类:
facilitated,pharmaco,cancer,diagnostics,Underlying,risks,emergence,ultrasmall,Cancer,therapy,fast,emerging,biomedical,paradigm,that,elevates,tential,identification,monitoring,targeting,post,treatment,response,analysis,superparamagnetic,iron,oxide,nanoparticles,SPION,tremendous,significance,because,their,inherited,surface,area,reactivity,biocompatibility,superior,contrast,properties,In,addition,brief,introduction,summarize,various,progressive,aspects,pertaining,production,emphasis,sustainable,biomimetic,approaches,Post,synthesis,particulate,alterations,terms,affinity,liquid,accessibility,highlighted,parameters,including,core,fusions,photosensitivity,photothermal,which,diverse,discussed,We,also,elaborate,concept,magnetism,selectively,focus,chemotherapeutics,tumors,sorting,purification,entities,elimination,toxins,Finally,while,addressing,toxicity,nanomaterials,advent,healthier,alternative,compatible,cellular,teractions,reviewed,summary,these,discussions,spotlight,versatility,integration,multi
AB值:
0.577595
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