典型文献
Light-guided tumor diagnosis and therapeutics:From nanoclusters to polyoxometalates
文献摘要：
Malignant tumors,with the characteristics of easy metastasis and recurrence,are a serious threat to health of mankind.It is urgent to develop promising clinical cancer targeted agents with combination of rapid diagnosis and efficient therapies.Compared with the conventional photosensitizing agents,the recent advances of nanoagents based on transition metal-oxide clusters possess unique structural and electronic properties,greatly improving cancer survival rate,meanwhile,keeping high contrast imaging.This review provides a brief introduction of metal-oxide clusters,including both nanoclusters to molecu-lar clusters,specifically polyoxometalates(POMs).Subsequently,biocompatibility of metal-oxide clusters is emphasized from aspects of endocytosis,macropinocytosis,and phagocytosis.Through the classification of late and early transition metals oxide clusters,recent outcomes of light-guided nanoagents are repre-sented with their intriguing chemical and optical properties in their diagnosing and photochemotherapy performance.It shed light on the summary of next generation multifunctional cancer targeting agents'developments as well as outlook of materials selection trends and research direction in the future.
文献关键词：
中图分类号：
作者姓名：
Xiaofeng Fan;Wei Pang;Hao Feng;Ruiyi Zhang;Wentao Zhu;Qiushi Wang;Jun Miao;Yiwen Li;Yanjun Liu;Xiaoqian Xu
作者机构：
Key Laboratory of Cell Biology,Ministry of Public Health and Key Laboratory of Medical Cell Biology,Ministry of Education,China Medical University,Shenyang 110122,China;Department of Ophthalmology,The First Affiliated Hospital of China Medical University,Shenyang 110001,China;Guangdong Provincial Key Laboratory of Catalysis,Shenzhen Grubbs Institute and Department of Chemistry,Southern University of Science and Technology,Shenzhen 518000,China;School of Materials Science and Engineering,Hubei University,Wuhan 430062,China;Department of Electrical and Electronic Engineering,Southern University of Science and Technology,Shenzhen 518000,China
文献出处：
引用格式：
[1]Xiaofeng Fan;Wei Pang;Hao Feng;Ruiyi Zhang;Wentao Zhu;Qiushi Wang;Jun Miao;Yiwen Li;Yanjun Liu;Xiaoqian Xu-.Light-guided tumor diagnosis and therapeutics:From nanoclusters to polyoxometalates)[J].中国化学快报（英文版）,2022(06):2783-2798
A类：
photosensitizing,nanoagents,photochemotherapy
B类：
Light,guided,diagnosis,therapeutics,From,nanoclusters,polyoxometalates,Malignant,tumors,characteristics,easy,metastasis,recurrence,serious,threat,health,mankind,It,urgent,promising,clinical,cancer,targeted,combination,rapid,efficient,therapies,Compared,conventional,recent,advances,transition,oxide,possess,unique,structural,electronic,properties,greatly,improving,survival,rate,meanwhile,keeping,high,contrast,imaging,This,review,provides,brief,introduction,including,both,molecu,lar,specifically,POMs,Subsequently,biocompatibility,emphasized,from,aspects,endocytosis,macropinocytosis,phagocytosis,Through,classification,early,metals,outcomes,light,repre,sented,their,intriguing,chemical,optical,diagnosing,performance,shed,summary,next,generation,multifunctional,targeting,developments,well,outlook,materials,selection,trends,research,direction,future
AB值：
0.633843
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