典型文献
Regulation of antiviral immune response by African swine fever virus(ASFV)
文献摘要：
African swine fever(ASF)is a highly contagious and acute hemorrhagic viral disease with a high mortality approaching 100％in domestic pigs.ASF is an endemic in countries in sub-Saharan Africa.Now,it has been spreading to many countries,especially in Asia and Europe.Due to the fact that there is no commercial vaccine available for ASF to provide sustainable prevention,the disease has spread rapidly worldwide and caused great economic losses in swine industry.The knowledge gap of ASF virus(ASFV)pathogenesis and immune evasion is the main factor to limit the development of safe and effective ASF vaccines.Here,we will summarize the mo-lecular mechanisms of how ASFV interferes with the host innate and adaptive immune responses.An in-depth understanding of ASFV immune evasion strategies will provide us with rational design of ASF vaccines.
文献关键词：
中图分类号：
作者姓名：
Xiaojie Zheng;Shengming Nie;Wen-Hai Feng
作者机构：
State Key Laboratory of Agrobiotechnology,College of Biological Sciences,China Agricultural University,Beijing,100193,China;Ministry of Agriculture Key Laboratory of Soil Microbiology,College of Biological Sciences,China Agricultural University,Beijing 100193,China;Department of Microbiology and Immunology,College of Biological Sciences,China Agricultural University,Beijing 100193,China
文献出处：
引用格式：
[1]Xiaojie Zheng;Shengming Nie;Wen-Hai Feng-.Regulation of antiviral immune response by African swine fever virus(ASFV))[J].中国病毒学,2022(02):157-167
A类：
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AB值：
0.573236
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