典型文献
Importation of SARS-CoV-2 Omicron variant in Beijing, China
文献摘要：
Omicron (B.1.1.529), the fifth variant of concern (VOC) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was firstly identified in November 2021 in South Africa. Omicron contains far more genome mutations than any other VOCs ever found, raising significant concerns about its increased transmissibility and immune evasion. Here, we report the importation of the Omicron variant into Beijing, China, in December 2021. Full-length genome sequences of five imported strains were obtained, with their genetic features characterized. Each strain contained 57 to 61 nucleotide substitutions, 39 deletions, and 9 insertions in the genome. Thirty to thirty-two amino acid changes were found in the spike proteins of the five strains. The phylogenetic tree constructed by the maximum likelihood method showed that all five imported genomes belonged to Omicron (BA.1) (alias of B.1.1.529.1), which is leading to the current surge of coronavirus disease 2019 (COVID-19) cases worldwide. The globally increased COVID-19 cases driven by the Omicron variant pose a significant challenge to disease prevention and control in China. Continuous viral genetic surveillance and increased testing among international travellers are required to contain this highly contagious variant.
文献关键词：
COVID-19;SARS-CoV-2;Omicron variant;Genomic characteristics
中图分类号：
作者姓名：
Li Fu;Liang Zhichao;Cui Shujuan;Lv Bing;Feng Zhaomin;Xu Hui;Jia Lei;Yang Peng;Wang Quanyi;Pan Yang;Zhang Daitao
作者机构：
Beijing Center for Disease Prevention and Control, Beijing 100013, China
文献出处：
引用格式：
[1]Li Fu;Liang Zhichao;Cui Shujuan;Lv Bing;Feng Zhaomin;Xu Hui;Jia Lei;Yang Peng;Wang Quanyi;Pan Yang;Zhang Daitao-.Importation of SARS-CoV-2 Omicron variant in Beijing, China)[J].生物安全与健康 （英文）,2022(03):150-153
A类：
Importation
B类：
SARS,CoV,Omicron,variant,Beijing,China,fifth,severe,acute,respiratory,syndrome,coronavirus,was,firstly,identified,November,South,Africa,contains,far,more,mutations,than,any,other,VOCs,found,raising,significant,concerns,about,its,increased,transmissibility,immune,evasion,Here,report,importation,into,December,Full,length,sequences,five,imported,strains,were,obtained,their,features,characterized,Each,contained,nucleotide,substitutions,deletions,insertions,Thirty,thirty,two,amino,acid,changes,spike,proteins,phylogenetic,tree,constructed,by,maximum,likelihood,method,showed,that,genomes,belonged,BA,alias,which,leading,current,surge,disease,cases,worldwide,globally,driven,pose,challenge,prevention,control,Continuous,viral,surveillance,testing,among,international,travellers,are,required,this,highly,contagious,Genomic,characteristics
AB值：
0.6397
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
