典型文献
Methods for monitoring cancer cell pyroptosis
文献摘要：
Pyroptosis is a form of proinflammatory cell death that depends on the gasdermin family of proteins.The main features of pyroptosis are altered membrane permeability, cell swelling, membrane rupture, and the ability to mobilize a strong immune response. The relationship between pyroptosis and cancer has become a popular topic in immunological research. Multiple strategies for inducing pyroptosisincancercellshavebeendevelopedforcancertherapy,includingchemotherapy,smallmoleculedrugs,andnanomedicines. In this review, we systematically discuss recent advances in research on the mechanisms of pyroptosis, and compare pyroptosis with apoptosis and necroptosis from several aspects. The development of various experimental systems has accompanied rapid progress in this field, but little consensus on monitoring pyroptosis is currently available.We focus on techniques commonly used to monitor pyroptosis, and describe future techniques that may be used to increase our knowledge in this field. Overall, the advancement of pyroptosis detection methods will help researchers to better investigate the relationships between pyroptosis and various cancers,and should provide insights into the use of these promising tools for cancer treatments.
文献关键词：
中图分类号：
作者姓名：
Shuo Wang;Yuantong Liu;Lu Zhang;Zhijun Sun
作者机构：
The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine, Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China;Department of Oral Maxillofacial-Head Neck Oncology, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China
文献出处：
引用格式：
[1]Shuo Wang;Yuantong Liu;Lu Zhang;Zhijun Sun-.Methods for monitoring cancer cell pyroptosis)[J].癌症生物学与医学（英文版）,2022(04):398-414
A类：
pyroptosisincancercellshavebeendevelopedforcancertherapy,includingchemotherapy,smallmoleculedrugs,andnanomedicines
B类：
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AB值：
0.580098
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