典型文献
Symphony of nanomaterials and immunotherapy based on the cancer-immunity cycle
文献摘要：
The immune system is involved in the initiation and progression of cancer.Research on cancer and immunity has contributed to the development of several clinically successful immunotherapies.These immunotherapies often act on a single step of the cancer-immunity cycle.In recent years,the discovery of new nanomaterials has dramatically expanded the functions and potential applications of nanomaterials.In addition to acting as drug-delivery platforms,some nanomaterials can induce the immunogenic cell death(ICD)of cancer cells or regulate the profile and strength of the immune response as immunomodulators.Based on their versatility,nanomaterials may serve as an integrated platform for multiple drugs or therapeu-tic strategies,simultaneously targeting several steps of the cancer-immunity cycle to enhance the outcome of anticancer immune response.To illustrate the critical roles of nanomaterials in cancer immunotherapies based on cancer-immunity cycle,this review will comprehensively describe the crosstalk between the im-mune system and cancer,and the current applications of nanomaterials,including drug carriers,ICD in-ducers,and immunomodulators.Moreover,this review will provide a detailed discussion of the knowledge regarding developing combinational cancer immunotherapies based on the cancer-immunity cycle,hoping to maximize the efficacy of these treatments assisted by nanomaterials.
文献关键词：
中图分类号：
作者姓名：
Qianqian Li;Zhaoqing Shi;Fan Zhang;Weiwei Zeng;Dunwan Zhu;Lin Mei
作者机构：
School of Pharmaceutical Sciences(Shenzhen),Sun Yat-sen University,Shenzhen 518107,China;Tianjin Key Laboratory of Biomedical Materials,Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences & Peking Union Medical College,Tianjin 300192,China
文献出处：
引用格式：
[1]Qianqian Li;Zhaoqing Shi;Fan Zhang;Weiwei Zeng;Dunwan Zhu;Lin Mei-.Symphony of nanomaterials and immunotherapy based on the cancer-immunity cycle)[J].药学学报（英文版）,2022(01):107-134
A类：
immunomodulators,ducers
B类：
Symphony,nanomaterials,immunotherapy,immunity,cycle,immune,system,involved,initiation,progression,Research,has,contributed,development,several,clinically,successful,immunotherapies,These,often,single,In,recent,years,discovery,new,dramatically,expanded,functions,potential,applications,addition,acting,delivery,platforms,some,induce,immunogenic,death,ICD,cells,regulate,profile,strength,response,Based,their,versatility,may,serve,integrated,multiple,drugs,therapeu,strategies,simultaneously,targeting,steps,enhance,outcome,anticancer,To,illustrate,critical,roles,this,review,will,comprehensively,describe,crosstalk,between,current,including,carriers,Moreover,provide,detailed,discussion,knowledge,regarding,developing,combinational,hoping,maximize,efficacy,these,treatments,assisted,by
AB值：
0.505579
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