典型文献
Diverse sesquiterpenoids from Litsea lancilimba Merr.with potential neuroprotective effects against H2O2-induced SH-SY5Y cell injury
文献摘要：
Five undescribed sesquiterpenoids(1-5),and nine known sesquiterpenoids(6-14)were obtained from the fruits of Lit-sea lancilimba Merr.by LC-MS/MS molecular networking strategies.Litsemene A(1)possessed a unique 8-member ring through un-expected cyclization of the methyl group on C-10 of guaiane.Their structures were elucidated by spectroscopic techniques including IR,UV,NMR,HR-ESI-MS,and their absolute configurations were assigned by ECD calculations.All isolated sesquiterpenoids were analyzed by bioinformatics and evaluated for their neuroprotective effects against H2O2-induced injury in human neuroblastoma SH-SY5Y cells.
文献关键词：
中图分类号：
作者姓名：
ZHANG Yi-Jie;BAI Ming;LI Jia-Yi;QIN Shu-Yan;LIU Yu-Yang;HUANG Xiao-Xiao;ZHENG Jiang;SONG Shao-Jiang
作者机构：
Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development,Liaoning Province;En-gineering Research Center of Natural Medicine Active Molecule Research & Development,Liaoning Province;Key Laboratory of Natural Bioactive Compounds Discovery & Modification,Shenyang;School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China;Wuya College of Innovation,Shenyang Pharmaceutical University,Shenyang 110016,China;State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University,Guiyang 550004,China
文献出处：
引用格式：
[1]ZHANG Yi-Jie;BAI Ming;LI Jia-Yi;QIN Shu-Yan;LIU Yu-Yang;HUANG Xiao-Xiao;ZHENG Jiang;SONG Shao-Jiang-.Diverse sesquiterpenoids from Litsea lancilimba Merr.with potential neuroprotective effects against H2O2-induced SH-SY5Y cell injury)[J].中国天然药物,2022(09):701-711
A类：
Litsemene
B类：
Diverse,sesquiterpenoids,from,Litsea,lancilimba,Merr,potential,neuroprotective,effects,against,H2O2,induced,SH,SY5Y,injury,Five,undescribed,nine,known,were,obtained,fruits,by,LC,molecular,networking,strategies,possessed,unique,member,ring,through,expected,cyclization,methyl,group,guaiane,Their,structures,elucidated,spectroscopic,techniques,including,UV,NMR,ESI,their,absolute,configurations,assigned,ECD,calculations,All,isolated,analyzed,bioinformatics,evaluated,human,neuroblastoma,cells
AB值：
0.634256
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
