Chun Zhao;Mei-yun Xin;Jing Li;Jin-fang Zhao;Yu-juan Wang;Wei Wang;Qian Gao;Jie Chen;Qi-wei Wang;You-peng Jin-Department of Pediatric Intensive Care Unit,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China;Department of Pediatrics,Affiliated Hospital of Jining Medical University,Jining 272129,China;Department of Pediatrics,Qingdao Women and Children Hospital,Qingdao 266034,China;Department of Pediatric Intensive Care Unit,Shandong Provincial Hospital,Cheeloo College of Medicine,Shandong University,Jinan 250021,China

Wen-Rui XU;Jun-Bao Du;Hong-Fang Jin-Department of Pediatrics,Peking University First Hospital,No.1,Xi'an-Men Street,West District,Beijing 100034,China;Key Lab of Molecular Cardiovascular Sciences,Ministry of Education,Beijing,China

Sheng-Bo Fang;Yan-Qing Song;Chun-Yan Zhang;Li-Bo Wang-Department of Pharmacy,First Hospital of Jilin University,Changchun,China;Department of Pediatric Gastroenterology Unit,First Hospital of Jilin University,71 Xinmin Street,Changchun 130021,China

Martina P.Neininger;Sarah Jeschke;Lisa M.Kiesel;Thilo Bertsche;Astrid Bertsche-Clinical Pharmacy,Institute of Pharmacy,Medical Faculty,Leipzig University and Drug Safety Center,Leipzig University and University Hospital,Bruederstrasse 32,04103 Leipzig,Germany;University Hospital for Children and Adolescents,Neuropediatrics,Ernst-Heydemann-Str.8,18057 Rostock,Germany

Alanood S.Algarni;Njoud M.Alamri;Noor Z.Khayat;Raghad A.Alabdali;Rawabi S.Alsubhi;Shahad H.Alghamdi-Department of Pharmacology and Toxicology,Faculty of Pharmacy,Pharmacy Collage,Umm Al-Qura University,Makkah 21955,Saudi Arabia;Pharmacy Collage,Umm Al-Qura University,Makkah,Saudi Arabia

Madeline Borel;Luyu Xie;Olivia Kapera;Adrian Mihalcea;Jeffrey Kahn;Sarah E.Messiah-School of Public Health,University of Texas Health Science Center,Dallas Campus,2777 N Stemmons Fwy,Dallas,TX 75207,USA;Center for Pediatric Population Health,University of Texas Health School of Public Health and Children's Health System of Texas,Dallas,TX,USA;School of Public Health,University of Texas Health Science Center,Austin Campus,Austin,TX,USA;School of Public Health,University of Texas Health Science Center,Houston Campus,Houston,TX,USA;Department of Pediatrics,University of Texas Southwestern Medical Center,Dallas,TX,USA;Children's Health System of Texas,Dallas,TX,USA

Stefan Bittmann-Department of Pediatrics,Medical and Finance Center Epe,Ped Mind Institute(PMI),Hindenburgring 4,48599 Gronau,Germany

Somayeh Fatahi;Amirhossein Hosseini;Mohammad Hassan Sohouli;Aliakbar Sayyari;Katayoun Khatami;Zahra Fazeli Farsani;Hamzeh Amiri;Naghi Dara;Ivan G.O.de Souza;Heitor O.Santos-Pediatric Gastroenterology,Hepatology,and Nutrition Research Center,Research Institute for Children's Health,Shahid Beheshti University of Medical Sciences,Tehran,Iran;Student Research Committee,Faculty of Public Health Branch,Iran University of Medical Sciences,Tehran,Iran;Student Research Committee,Department of Clinical Nutrition and Dietetics,Faculty of Nutrition and Food Technology,Shahid Beheshti University of Medical Sciences,Tehran,Iran;School of Health Sciences,Universidade Salvador(UNIFACS),Salvador,Bahia,Brazil;School of Medicine,Federal University of Uberlandia(UFU),Uberlandia,Minas Gerais,Brazil

Wen-Jia Zhao;Jiang-Hong Deng;Cai-Feng Li-Department of Rheumatology,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,No.56,Nan Li Shi Road,Beijing 100045,China

Char Leung;Luisamanda Selle;Karina Mary de Paiva;Patricia Haas-School of Clinical Medicine,Addenbrooke's Hospital,University of Cambridge,Hills Road,Cambridge CB2 0QQ,UK;Department of Speech,Language and Hearing Sciences,Federal University of Santa Catarina,Florianópolis,Brazil

Alvin Salim;Evelyn Hemme Tambunan-Universitas Advent Indonesia,Bandung 40559,Indonesia

Li Hua;Wang Yong;Zhao Changying;Liu Jian;Zhang Lei;Li Anyuan-Department of Gastroenterology, Cheeloo Children's Hospital, Shandong University, Jinan, Shandong 250022, China;Department of Laboratory Medicine, School of Stomatology and Medicine, Foshan University, Chancheng District, Foshan, Guangdong 528000, China;Jinan Institute of Paediatric Medicine, Cheeloo Children's Hospital, Shandong University, Jinan, Shandong 250022, China;Microbiome-X, National Institute of Health Data Science of China, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250002, China;Department of Traditional Chinese Medicine, Shandong Provincial Hospital, Shandong University, Jinan, Shandong 250021, China

Li Jiaqing;Mao Dandan;Liu Shuoshuo;Liu Ping;Tian Jing;Xue Chenhong;Liu Xiaojing;Qi Ruiqun;Bai Bingxue;Nie Jianjun;Ye Siqi;Wang Yu;Li Yuye;Sun Qing;Tao Juan;Guo Shuping;Fang Hong;Wang Jianqin;Mu Qiri;Liu Quanzhong;Ding Yan;Zhang Jianzhong-Department of Dermatology, Peking University People’s Hospital, Beijing 100044, China;Department of Dermatology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China;Department of Dermatology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China;Optical Medicine Institute of Tongji University in Shanghai Skin Disease Hospital, Shanghai 200071, China;Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China;Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;Department of Dermatology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, China;Department of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, China;Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China;Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650031, China;Department of Dermatology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China;Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China;Department of Dermatology, First Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China;Department of Dermatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China;Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, Guangdong 510095, China;Department of Dermatology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia 010017, China;Department of Dermatology, Tianjin Medical University General Hospital, Tianjin 300052, China;Department of Dermatology, Hainan Provincial Hospital of Skin Disease, Haikou, Hainan 570206, China

Liu Yunfei;Dong Yanhui;Yan Xiaojin;Ma Ning;Dang Jiajia;Zhang Jingshu;Zhong Panliang;Li Luo;Zou Zhiyong;Song Yi;Ma Jun-Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China;The University of Melbourne, Melbourne School of Population and Global Health, Parkville, VIC 3010, Australia

Abdullahi Tunde Aborode;Abideen Opeyemi Olasupo;Taibat Aduragba Hussain;Abayomi Oyeyemi Ajagbe-Healthy African Platform,Research and Development,Ibadan,Nigeria;Brain Builders Youth Development Initiative,Research and Education,Ilorin,Nigeria;Rising Child Foundation,Research and Education,Nigeria;Department of Anatomy,Faculty of Basic Medical Sciences,College of Health Sciences,Nile University of Nigeria,P.M.B.900001,Abuja,Nigeria

Soumya Ranjan Satapathy;Rudra Narayan Sahoo-School of Pharmaceutical Sciences,Siksha'O'Anusandhan(Deemed to be University),Bhubaneswar,India

Claudio Bruno Silva de Oliveira;Joelma Maria de Araújo Andrade;Jonas Ivan Nobre Oliveira-Pediatric Hospital Maria Alice Fernandes,Natal,Rio Grande do Norte,Brazil;Blood Center Dalton Cunha,Natal,Rio Grande do Norte,Brazil;Federal University of Rio Grande do Norte,Department of Biophysics and Pharmacology,Natal,Rio Grande do Norte,Brazil

Cheng Jiangli;Ma Aijia;Dong Meiling;Zhou Yongfang;Wang Bo;Xue Yang;Wang Peng;Yang Jing;Kang Yan-Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China

Jing-Yu Wang;Tian-Ning Li;Chun-Lei Zhou;Jie Zhao;Meng Wang;Yuan Wang;Yan Jiang;He-Nan Dong;Qian-Ru Qi;Hong Mu-Department of Clinical Lab,Tianjin First Central Hospital,Tianjin,300192,China;The First Central Clinical College,Tianjin Medical University,Tianjin,300192,China;Department of Clinical Lab,Tianjin Children's Hospital,Tianjin,300074,China

Jinrong Liu;Rongfang Shen;Lin Feng;Shujun Cheng;Jun Chen;Ting Xiao;Shunying Zhao-Department of Respiratory Medicine,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China;State Key Laboratory of Molecular Oncology,Department of Etiology and Carcinogenesis,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;Beijing Engineering Research Center of Pediatric Surgery,Engineering and Transformation Center Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China