Background::Urticaria is a common skin disease characterized by episodes of wheals, and it has a negative effect on patients’ quality of life. Large-scale population-based epidemiological studies of urticaria are scarce in China. The aim of this survey was to determine the prevalence, clinical forms, and risk factors of urticaria in the Chinese population.Methods::This survey was conducted in 35 cities from 31 provinces, autonomous regions, and municipalities of China. Two to three communities in each city were selected in this investigation. Participants completed questionnaires and received dermatological examinations. We analyzed the prevalence, clinical forms, and risk factors of urticaria.Results::In total, 44,875 questionnaires were distributed and 41,041 valid questionnaires were collected (17,563 male and 23,478 female participants). The lifetime prevalence of urticaria was 7.30%, with 8.26% in female and 6.34% in male individuals ( P < 0.05). The point prevalence of urticaria was 0.75%, with 0.79% in female and 0.71% in male individuals ( P < 0.05). Concomitant angioedema was found in 6.16% of patients. Adults had a higher prevalence of urticaria than adolescents and children. Living in urban areas, exposure to pollutants, an anxious or depressed psychological status, a personal and family history of allergy, thyroid diseases, and Helicobacter pylori infection were associated with a higher prevalence of urticaria. Smoking was correlated with a reduced risk of urticaria. Conclusion::This study demonstrated that the lifetime prevalence of urticaria was 7.30% and the point prevalence was 0.75% in the Chinese population; women had a higher prevalence of urticaria than men. Various factors were correlated with urticaria.

Urticaria;Prevalence;Risk factor;China

Li Jiaqing;Mao Dandan;Liu Shuoshuo;Liu Ping;Tian Jing;Xue Chenhong;Liu Xiaojing;Qi Ruiqun;Bai Bingxue;Nie Jianjun;Ye Siqi;Wang Yu;Li Yuye;Sun Qing;Tao Juan;Guo Shuping;Fang Hong;Wang Jianqin;Mu Qiri;Liu Quanzhong;Ding Yan;Zhang Jianzhong

Department of Dermatology, Peking University People’s Hospital, Beijing 100044, China;Department of Dermatology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China;Department of Dermatology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China;Optical Medicine Institute of Tongji University in Shanghai Skin Disease Hospital, Shanghai 200071, China;Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China;Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China;Department of Dermatology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, China;Department of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510120, China;Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China;Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650031, China;Department of Dermatology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China;Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China;Department of Dermatology, First Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China;Department of Dermatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China;Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, Guangdong 510095, China;Department of Dermatology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia 010017, China;Department of Dermatology, Tianjin Medical University General Hospital, Tianjin 300052, China;Department of Dermatology, Hainan Provincial Hospital of Skin Disease, Haikou, Hainan 570206, China

中华医学杂志（英文版）

[1]Li Jiaqing;Mao Dandan;Liu Shuoshuo;Liu Ping;Tian Jing;Xue Chenhong;Liu Xiaojing;Qi Ruiqun;Bai Bingxue;Nie Jianjun;Ye Siqi;Wang Yu;Li Yuye;Sun Qing;Tao Juan;Guo Shuping;Fang Hong;Wang Jianqin;Mu Qiri;Liu Quanzhong;Ding Yan;Zhang Jianzhong-.Epidemiology of urticaria in China: a population-based study)[J].中华医学杂志（英文版）,2022(11):1369-1375

Urticaria,wheals

Epidemiology,urticaria,China,population,study,Background,common,skin,characterized,by,episodes,has,negative,effect,patients,quality,Large,scale,epidemiological,studies,scarce,aim,this,survey,was,determine,prevalence,clinical,forms,risk,factors,Chinese,Methods,This,conducted,cities,from,provinces,autonomous,regions,municipalities,Two,three,communities,each,city,were,selected,investigation,Participants,completed,questionnaires,received,dermatological,examinations,We,analyzed,Results,In,total,distributed,valid,collected,female,participants,lifetime,individuals,point,Concomitant,angioedema,found,Adults,had,higher,than,adolescents,children,Living,urban,areas,exposure,pollutants,anxious,depressed,psychological,status,personal,family,history,allergy,thyroid,diseases,Helicobacter,pylori,infection,associated,Smoking,correlated,reduced,Conclusion,demonstrated,that,women,Various,Prevalence,Risk

0.510361