典型文献
Research progress in drug therapy of juvenile idiopathic arthritis
文献摘要：
Background Juvenile idiopathic arthritis(JIA)is the most common chronic rheumatic disease in children.With the gradual expansion of the incidence of JIA in the population,the pathogenesis and treatment of JIA were further explored and ana-lyzed,and JIA has achieved some success in drug therapy.Data sources A systemic literature search was conducted on PubMed,Cochrane Library,EMBASE,ISI Web of Science,the US National Institutes of Health Ongoing Trials Register,and the EU Clinical Trials Register.Through the searching of clinical trials of JIA in recent years,we summarized the progress of the clinical treatment of JIA.Results The main treatment drugs for JIA include non-steroidal anti-inflammatory drugs,glucocorticoids,disease-modifying antirheumatic drugs and biological agents.So far,a variety of biological agents targeting the cytokines and receptors involved in its pathogenesis have been gradually approved for JIA in many countries.The application of biological agents in JIA showed good efficacy and safety,bringing unprecedented experience to children and adolescents with JIA.Conclusions The potential and advantages of biologic agents in the treatment of JIA are significant,and the application of biologic agents in the treatment of JIA will be more and more common.
文献关键词：
中图分类号：
作者姓名：
Wen-Jia Zhao;Jiang-Hong Deng;Cai-Feng Li
作者机构：
Department of Rheumatology,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,No.56,Nan Li Shi Road,Beijing 100045,China
文献出处：
引用格式：
[1]Wen-Jia Zhao;Jiang-Hong Deng;Cai-Feng Li-.Research progress in drug therapy of juvenile idiopathic arthritis)[J].世界儿科杂志（英文版）,2022(06):383-397
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