典型文献
Nature products of traditional Chinese medicine provide new ideas in γδ T cells for tumor immunotherapy
文献摘要:
Due to the unique features of innate immune cells, the role of γδ T cells in tumor immunity has gradually attracted more and more attention. Previous studies have found that γδ T cells play a dual role in tumor immunology:tumor-promoting and tumor-controlling. The anti-tumor therapy of γδ T cells has made remarkable success in clinical application. Especially in recent years, researchers have provided some novel effective ways such as γδ T cells exosomes and adoptive chimeric antigen receptor-γδT cells immunotherapy. However, some problems remain to be solved, such as low expansion rate, poor targeting, and tumor microenvironment limiting the effectiveness of γδ T immunotherapy. Traditional Chinese medicine is expected to play a positive role in the body immune-enhancing function, promoting the proliferation and activation of γδ T cells, and inducing the differentiation of γδ T cells. In this review, we summarize the recent research progress and urgent problems of γδT cells in anti-tumor immunotherapy. Moreover, some new strategies of γδT cells for tumor immunotherapy were proposed.
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作者姓名:
Paulina Atieno Duya;Yinxiao Chen;Liding Bai;Zhaodong Li;Jiaying Li;Rundong Chai;Yuhong Bian;Shuwu Zhao
作者机构:
Ministry of Health Kenya,Division of Traditional and Alternative Medicine,Kenya;Tianjin University of Traditional Chinese Medicine,Tianjin,China
文献出处:
引用格式:
[1]Paulina Atieno Duya;Yinxiao Chen;Liding Bai;Zhaodong Li;Jiaying Li;Rundong Chai;Yuhong Bian;Shuwu Zhao-.Nature products of traditional Chinese medicine provide new ideas in γδ T cells for tumor immunotherapy)[J].针灸和草药(英文),2022(02):78-83
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0.575782
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