典型文献
Role of allogeneic haematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukaemia in the era of immunotherapy
文献摘要：
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the standard of care for adult acute lymphoblastic leukemia (ALL) patients. In recent years, with the continuous development of immunotherapy, such as chimeric antigen receptor T cells, blinatumomab, and inotuzumab ozogamicin, a series of vital clinical studies have confirmed its high response rate and favorable outcomes for ALL. Although the emergence of immunotherapy has expanded relapsed or refractory (r/r) ALL patients' opportunities to receive allo-HSCT, allo-HSCT is associated with potential challenges. In this review, the role of allo-HSCT in the treatment of adult ALL in the era of immunotherapy will be discussed.
文献关键词：
Acute lymphoblastic leukemia;Allogeneic hematopoietic stem cell transplantation;Immunotherapy;Chimeric antigen receptor-T cells
中图分类号：
作者姓名：
Sun Wei;Huang Xiaojun
作者机构：
Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing 100044, China
文献出处：
引用格式：
[1]Sun Wei;Huang Xiaojun-.Role of allogeneic haematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukaemia in the era of immunotherapy)[J].中华医学杂志（英文版）,2022(08):890-900
A类：
inotuzumab,ozogamicin
B类：
Role,allogeneic,haematopoietic,stem,transplantation,treatment,adult,acute,lymphoblastic,leukaemia,immunotherapy,Allogeneic,hematopoietic,HSCT,currently,standard,care,leukemia,ALL,patients,In,recent,years,continuous,development,such,chimeric,antigen,receptor,cells,blinatumomab,series,vital,clinical,studies,have,confirmed,its,high,response,rate,favorable,outcomes,Although,emergence,has,expanded,relapsed,refractory,opportunities,receive,associated,potential,challenges,this,review,role,will,be,discussed,Acute,Immunotherapy,Chimeric
AB值：
0.529729
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