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典型文献
Positive effect of ethanol-induced Lactococcus lactis on alcohol metabolism in mice
文献摘要:
It is well known that exposure to environmental stresses could enhance the adaptability of bacteria and up-regulate the expression of a variety of oxidative stress-related genes and antioxidant enzymes. It is unclear whether the adaptability of microorganisms formed naturally in special environments could transfer to other organisms. The study aimed to evaluate the effects of untreated and ethanol-induced Lactococcus lactis intracellular extracts (U-IE and E-IE) on alcohol metabolism in mice. The positive effects of E-IE on alcohol metabolism in mice were revealed by the enhanced latency of loss of righting reflex (LORR), the reduced duration of LORR, the decrease of blood alcohol concentration, as well as the elevation of alcohol dehydrogenase (ADH) activities in the stomach and liver tissues. Furthermore, the potential benefits of E-IE on the liver were evaluated by biochemical parameters including the activities of serum transaminase, the levels of antioxidant enzymes, and the pathological changes of liver tissue. The present work put forward a new point that appropriate ethanol stress could enhance the intracellular ADH activity of L. lactis, and its intracellular extracts could continue to enhance alcohol metabolism in mice.
文献关键词:
作者姓名:
Sisi Chen;Shimin Jia;Keke Suo;Qiaozhen Kang;Limin Hao;Laizheng Lu;Xin Liu;Jinyong Huang;Jike Lu
作者机构:
School of Life Sciences,Zhengzhou University,Zhengzhou 450001,China;Physical Education College,Zhengzhou University,Zhengzhou 450001,China;The Quartermaster Research Institute of Engineering and Technology,Academy of Military Sciences PLA China,Beijing 100010,China;Zhengzhou Mindtek Biotechnology Co.,Ltd.,Zhengzhou 450001,China;School of Agricultural Sciences,Zhengzhou University 450001,China
引用格式:
[1]Sisi Chen;Shimin Jia;Keke Suo;Qiaozhen Kang;Limin Hao;Laizheng Lu;Xin Liu;Jinyong Huang;Jike Lu-.Positive effect of ethanol-induced Lactococcus lactis on alcohol metabolism in mice)[J].食品科学与人类健康(英文),2022(05):1183-1190
A类:
righting,LORR
B类:
Positive,ethanol,induced,Lactococcus,lactis,alcohol,metabolism,mice,It,well,known,that,exposure,environmental,stresses,could,adaptability,bacteria,up,regulate,expression,variety,oxidative,related,genes,antioxidant,enzymes,unclear,whether,microorganisms,formed,naturally,special,environments,transfer,other,study,aimed,effects,untreated,intracellular,extracts,IE,positive,were,revealed,by,enhanced,latency,loss,reflex,reduced,duration,decrease,blood,concentration,elevation,dehydrogenase,ADH,activities,stomach,liver,tissues,Furthermore,potential,benefits,evaluated,biochemical,parameters,including,serum,transaminase,levels,pathological,changes,present,work,put,forward,new,point,appropriate,activity,continue
AB值:
0.498491
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