典型文献
Ameliorative effect of scutellarin on acute alcohol brain injury in mice
文献摘要：
Drinking culture has high significance in both China and the world, whether in the entertainment sector or in social occasions;according to the World Health Organization's 2018 Global Alcohol and Health Report, about 3 million people died from excessive drinking in 2016, accounting for 5.3％ of the total global deaths that year. Oxidative stress and inflam-mation are the most common pathological phenomena caused by alcohol abuse (Snyder et al., 2017). Scutel-larin, a kind of flavonoid, is one of the main active ingredients extracted from breviscapine. It exerts anti-inflammatory, antioxidant, and vasodilation effects, and has been used to treat cardiovascular diseases and alcoholic liver injury. Although scutellarin can effect-ively alleviate multi-target organ injury induced by different forms of stimulation, its protective effect on alcoholic brain injury has not been well-defined. There-fore, the present study established an acute alcohol mice brain injury model to explore the effect of scutellarin on acute alcoholic brain injury. The study was carried out based on the targets of oxidative stress and inflam-mation, which is of great significance for the targeted therapy of clinical alcohol diseases.
文献关键词：
中图分类号：
作者姓名：
Tianmeng ZHANG;Kun WANG;Hui FAN;Qiankun YANG;Xiao ZHANG;Feixue LIU;Xin FENG;Yi CHEN;Daoyang TENG;Panpan ZHAO;Jingquan DONG
作者机构：
Jiangsu Key Laboratory of Marine Bioresources and Environment,Co-Innovation Center of Jiangsu Marine Bio-Industry Technology,Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening,Jiangsu Ocean University,Lianyungang 222005,China;Department of Laboratory Medicine,the Second People's Hospital of Lianyungang City,Lianyungang 222000,China;Key Laboratory of Zoonosis of Ministry of Education,College of Veterinary Medicine,Jilin University,Changchun 130062,China
引用格式：
[1]Tianmeng ZHANG;Kun WANG;Hui FAN;Qiankun YANG;Xiao ZHANG;Feixue LIU;Xin FENG;Yi CHEN;Daoyang TENG;Panpan ZHAO;Jingquan DONG-.Ameliorative effect of scutellarin on acute alcohol brain injury in mice)[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2022(03):258-264,后插1-后插2
A类：
Ameliorative,scutellarin,Scutel,larin,breviscapine
B类：
acute,brain,injury,mice,Drinking,culture,has,high,significance,both,China,world,whether,entertainment,sector,social,occasions,according,World,Health,Organization,Global,Alcohol,Report,about,million,people,died,from,excessive,drinking,accounting,total,global,deaths,that,year,Oxidative,stress,mation,are,most,common,pathological,phenomena,caused,by,abuse,Snyder,kind,flavonoid,one,main,active,ingredients,extracted,It,exerts,inflammatory,antioxidant,vasodilation,effects,been,treat,cardiovascular,diseases,alcoholic,liver,Although,ively,alleviate,multi,organ,induced,different,forms,stimulation,its,protective,not,well,defined,There,fore,present,study,established,model,explore,was,carried,targets,oxidative,which,great,targeted,therapy,clinical
AB值：
0.572696
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