首站-论文投稿智能助手
典型文献
How physical and motor training affect cognitive performance:lessons from an inflammatory molecule
文献摘要:
Our phenotype includes not only physical features,but also behavioral outputs such as motor schemes and learned skills,and is the result of a complex interaction between genetic background and environment.In fact,a good fraction of last decades'biomedical efforts were dedicated to understanding how different elements(e.g.,genetic polymorphisms,lifestyle components)participate in this interplay,ultimately contributing to affect a given phenotype up to the point of steering it towards pathology.Genetic and epigenetic elements are relatively easy to analyze individually using a reductionist approach,for instance via loss-or gain-of-function studies in cellular and animal models;the effects of nutrients,drugs,pollutants can be similarly tested as single specific stimuli.Not as easy is to establish in rigorous terms and to understand the molecular mechanisms through which different levels of education,social interaction,exposure to a playful environment,psychological stress,to voluntary physical activity,may impact our brain phenotype,whose combined complexity is hard to reproduce in the experimental setting.
文献关键词:
作者姓名:
Margherita Maffei;Marco Mainardi
作者机构:
Institute of Clinical Physiology,National Research Council(IFC-CNR),and Obesity/Lipodystrophies Center,Pisa University Hospital,Pisa,Italy;Neuroscience Institute,National Research Council(IN-CNR),Pisa,Italy
引用格式:
[1]Margherita Maffei;Marco Mainardi-.How physical and motor training affect cognitive performance:lessons from an inflammatory molecule)[J].中国神经再生研究(英文版),2022(12):2689-2690
A类:
reductionist,playful
B类:
How,physical,motor,training,affect,cognitive,performance,lessons,from,inflammatory,molecule,Our,phenotype,includes,only,features,also,behavioral,outputs,such,schemes,learned,skills,result,interaction,between,background,environment,In,fact,good,fraction,last,decades,biomedical,efforts,were,dedicated,understanding,how,different,elements,polymorphisms,lifestyle,components,participate,this,interplay,ultimately,contributing,given,up,point,steering,towards,pathology,Genetic,epigenetic,are,relatively,easy,analyze,individually,using,approach,instance,via,loss,gain,function,studies,cellular,animal,models,effects,nutrients,drugs,pollutants,can,similarly,tested,single,specific,stimuli,Not,establish,rigorous,terms,molecular,mechanisms,through,which,levels,education,social,exposure,psychological,stress,voluntary,activity,may,impact,our,brain,whose,combined,complexity,hard,reproduce,experimental,setting
AB值:
0.726528
相似文献
Mongolian medicine in treating type 2 diabetes mellitus combined with nonalcoholic fatty liver disease via FXR/LXR-mediated P2X7R/NLRP3/NF-κB pathway activation
Shuyin Bao;Xiuzhi Wang;Qianqian Ma;Chengxi Wei;Jixing Nan;Wuliji Ao-Institute of Pharmaceutical Chemistry and Pharmacology,Inner Mongolia Minzu University,Tongliao 028000,China;Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System,Tongliao 028000,China;Jilin Key Laboratory for Traditional Chinese Korean Medicine,College of Pharmacy,Yanbian University,Yanji 133002,China;Department of Medicines and Foods,Tongliao Vocational College,Tongliao 028000,China;Research and development center,Inner Mongolia Research Institute of Traditional Mongolian Medicine Engineering Technology,Tongliao 028000,China;Mongolian Medicine R&D National Local Union Engineering Research Center,Inner Mongolia Minzu University,Tongliao 028000,China
EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription
Xiaoqing Lu;Liwei An;Guangjian FanTi;Lijuan Zang;Weiyi Huang;Junjian Li;Jun Liu;Weiyu Ge;Yuwei Huang;Jingxuan Xu;Shaoqian Du;Yuan Cao;Tianhao Zhou;Huijing Yin;Li Yu;Shi Jiao;Hongxia Wang-State Key Laboratory of Oncogenes and Related Genes,Department of Oncology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China;Department of Breast Surgery,Shanxi Cancer Hospital,Chinese Academy of Medical Sciences,Taiyuan,Shanxi,China;Department of Medical Ultrasound,Shanghai Tenth People's Hospital,Tongji University Cancer Center,School of Medicine,Tongji University,Shanghai,China;Precision Research Center for Refractory Diseases,Institute for Clinical Research,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China;Department of Pathology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China;State Key Laboratory of Membrane Biology,Tsinghua-Peking University Joint Center for Life Sciences,School of Life Science,Tsinghua University,Beijing,China;State Key Laboratory of Genetic Engineering,School of Life Sciences,Fudan University,Shanghai,China
Treatment of autosomal recessive hearing loss via in vivo CRISPR/Cas9-mediated optimized homology-directed repair in mice
Xi Gu;Xinde Hu;Daqi Wang;Zhijiao Xu;Fang Wang;Di Li;Geng-lin Li;Hui Yang;Huawei Li;Erwei Zuo;Yilai Shu-ENT institute and Department of Otorhinolaryngology,Eye & ENT Hospital,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Fudan University,Shanghai,China;Institutes of Biomedical Sciences,Fudan University,Shanghai,China;Department of Otolaryngology,the First Affiliated Hospital of Fujian Medical University,Fuzhou,China;NHC Key Laboratory of Hearing Medicine(Fudan University),Shanghai,China;Institute of Neuroscience,State Key Laboratory of Neuroscience,Key Laboratory of Primate Neurobiology,CAS Center for Excellence in Brain Science and Intelligence Technology,Shanghai Research Center for Brain Science and Brain-Inspired Intelligence,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai,China;State Key Lab for Conservation and Utilization of Subtropical Agric-Biological Resources,Guangxi University,Nanning,China;Shenzhen Branch,Guangdong Laboratory for Lingnan Modern Agriculture,Genome Analysis Laboratory of the Ministry of Agriculture,Agricultural Genomics Institute at Shenzhen,Chinese Academy of Agricultural Sciences,Shenzhen,China;The Institutes of Brain Science and the Collaborative Innovation Center for Brain Science,Fudan University,Shanghai,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。