典型文献
Nanofluidics for sub-single cellular studies:Nascent progress,critical technologies,and future perspectives
文献摘要：
In the field of cell studies,there is a burgeoning trend to further downscale the investigation from a single-cell level to a sub-single-cell level.Subcellular matter is the basic content in cells and correlates with cell heterogeneity.Sub-single cellular studies focus on the subcellular matter in single cells and aim to understand the details and heterogeneity of individual cells in terms of the subcellular matter or even at the single component/vesicle/molecule level.Hence,sub-single cellular studies can provide deeper in-sights into fundamental cell biology and the development of new diagnostic and therapeutic technologies and applications.Nonetheless,the contents of a single cell are not only ultra-small in volume but also ex-tremely complex in composition,far exceeding the capabilities of most tools used in current cell studies.We believe that nanofluidics holds great potential in providing ideal tools for sub-single cellular studies,not only because of their capability to handle femtoliter/attoliter-scale samples,but also because of their possibility to manipulate and analyze subcellular matters at the single component/vesicle/molecule level in a high-throughput manner.In this review,we summarize the efforts in the field of nanofluidics for sub-single cellular studies,focusing on nascent progress and critical technologies that have the poten-tial to overcome the technical bottlenecks.Some challenges and future opportunities to integrate with information sciences are also discussed.
文献关键词：
中图分类号：
作者姓名：
Jinbin Yang;Yan Xu
作者机构：
Department of Chemical Engineering,Graduate School of Engineering,Osaka Prefecture University,Sakai,Osaka 599-8570,Japan;Japan Science and Technology Agency(JST),PRESTO,Kawaguchi,Saitama,332-0012,Japan;NanoSquare Research Institute,Research Center for the 21st Century,Organization for Research Promotion,Osaka Prefecture University,Sakai,Osaka 599-8570,Japan
文献出处：
引用格式：
[1]Jinbin Yang;Yan Xu-.Nanofluidics for sub-single cellular studies:Nascent progress,critical technologies,and future perspectives)[J].中国化学快报（英文版）,2022(06):2799-2806
A类：
Nanofluidics,Nascent,nanofluidics,femtoliter,attoliter
B类：
single,studies,progress,critical,technologies,future,perspectives,In,field,there,burgeoning,trend,further,downscale,investigation,from,level,Subcellular,basic,cells,correlates,heterogeneity,subcellular,aim,understand,details,individual,terms,even,component,vesicle,molecule,Hence,can,provide,deeper,sights,into,fundamental,biology,development,new,diagnostic,therapeutic,applications,Nonetheless,contents,are,not,only,ultra,small,volume,but,also,tremely,complex,composition,far,exceeding,capabilities,most,tools,used,current,We,believe,that,holds,great,potential,providing,ideal,because,their,capability,handle,samples,possibility,manipulate,analyze,matters,high,throughput,manner,this,review,we,summarize,efforts,focusing,nascent,have,overcome,technical,bottlenecks,Some,challenges,opportunities,integrate,information,sciences,discussed
AB值：
0.499603
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
