典型文献
Co-regulation of circadian clock genes and microRNAs in bone metabolism
文献摘要：
Mammalian bone is constantly metabolized from the embryonic stage, and the maintenance of bone health depends on the dynamic balance between bone resorption and bone formation, mediated by osteoclasts and osteoblasts. It is widely recognized that circadian clock genes can regulate bone metabolism. In recent years, the regulation of bone metabolism by non-coding RNAs has become a hotspot of research. MicroRNAs can participate in bone catabolism and anabolism by targeting key factors related to bone metabolism, including circadian clock genes. However, research in this field has been conducted only in recent years and the mechanisms involved are not yet well established. Recent studies have focused on how to target circadian clock genes to treat some diseases, such as autoimmune diseases, but few have focused on the co-regulation of circadian clock genes and microRNAs in bone metabolic diseases. Therefore, in this paper we review the progress of research on the co-regulation of bone metabolism by circadian clock genes and microRNAs, aiming to provide new ideas for the prevention and treatment of bone metabolic diseases such as osteoporosis.
文献关键词：
中图分类号：
作者姓名：
Tingting LI;Shihua ZHANG;Yuxuan YANG;Lingli ZHANG;Yu YUAN;Jun ZOU
作者机构：
School of Exercise and Health,Guangzhou Sport University,Guangzhou 510500,China;School of Kinesiology,Shanghai University of Sport,Shanghai 200438,China;College of Graduate Education,Shandong Sport University,Jinan 250102,China
引用格式：
[1]Tingting LI;Shihua ZHANG;Yuxuan YANG;Lingli ZHANG;Yu YUAN;Jun ZOU-.Co-regulation of circadian clock genes and microRNAs in bone metabolism)[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2022(07):529-546,中插1-中插3
A类：
anabolism
B类：
Co,regulation,circadian,clock,genes,microRNAs,bone,metabolism,Mammalian,constantly,metabolized,from,embryonic,stage,maintenance,health,depends,dynamic,balance,between,resorption,formation,mediated,by,osteoclasts,osteoblasts,It,widely,recognized,that,can,regulate,In,recent,years,coding,has,become,hotspot,research,MicroRNAs,participate,catabolism,targeting,key,factors,related,including,However,this,field,been,conducted,only,mechanisms,involved,are,not,yet,well,established,Recent,studies,have,focused,how,some,diseases,such,autoimmune,but,few,metabolic,Therefore,paper,review,progress,aiming,provide,new,ideas,prevention,treatment,osteoporosis
AB值：
0.504299
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
