典型文献
Pharmaceutical applications of framework nucleic acids
文献摘要：
DNA is a biological polymer that encodes and stores genetic information in all living organ-ism.Particularly,the precise nucleobase pairing inside DNA is exploited for the self-assembling of na-nostructures with defined size,shape and functionality.These DNA nanostructures are known as framework nucleic acids(FNAs)for their skeleton-like features.Recently,FNAs have been explored in various fields ranging from physics,chemistry to biology.In this review,we mainly focus on the recent progress of FNAs in a pharmaceutical perspective.We summarize the advantages and applications of FNAs for drug discovery,drug delivery and drug analysis.We further discuss the drawbacks of FNAs and provide an outlook on the pharmaceutical research direction of FNAs in the future.
文献关键词：
中图分类号：
作者姓名：
Liang Chen;Jie Zhang;Zhun Lin;Ziyan Zhang;Miao Mao;Jiacheng Wu;Qian Li;Yuanqing Zhang;Chunhai Fan
作者机构：
School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China;School of Chemistry and Chemical Engineering,Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine,Shanghai Jiao Tong University,Shanghai 200240,China;Institute of Molecular Medicine,Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine,Renji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China
文献出处：
引用格式：
[1]Liang Chen;Jie Zhang;Zhun Lin;Ziyan Zhang;Miao Mao;Jiacheng Wu;Qian Li;Yuanqing Zhang;Chunhai Fan-.Pharmaceutical applications of framework nucleic acids)[J].药学学报（英文版）,2022(01):76-91
A类：
nucleobase,nostructures,FNAs
B类：
Pharmaceutical,applications,framework,nucleic,acids,biological,polymer,that,encodes,stores,genetic,information,all,living,organ,ism,Particularly,precise,pairing,inside,exploited,self,assembling,defined,size,shape,functionality,These,nanostructures,are,known,their,skeleton,like,features,Recently,have,been,explored,various,fields,ranging,from,physics,chemistry,biology,In,this,review,we,mainly,focus,recent,progress,pharmaceutical,perspective,We,summarize,advantages,drug,discovery,delivery,analysis,further,discuss,drawbacks,provide,outlook,research,direction,future
AB值：
0.624024
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