典型文献
Potential use of a dried saliva spot(DSS)in therapeutic drug monitoring and disease diagnosis
文献摘要:
In recent years,scientific researchers have increasingly become interested in noninvasive sampling methods for therapeutic drug monitoring and disease diagnosis.As a result,dried saliva spot(DSS),which is a sampling technique for collecting dried saliva samples,has been widely used as an alternative matrix to serum for the detection of target molecules.Coupling the DSS method with a highly sensitive detection instrument improves the efficiency of the preparation and analysis of biological samples.Furthermore,dried blood spots,dried plasma spots,and dried matrix spots,which are similar to those of the DSS method,are discussed.Compared with alternative biological fluids used in dried spot methods,including serum,tears,urine,and plasma,saliva has the advantage of convenience in terms of sample collection from children or persons with disabilities.This review aims to provide integral strategies and guidelines for dried spot methods to analyze biological samples by illustrating several dried spot methods.Herein,we summarize recent advancements in DSS methods from June 2014 to March 2021 and discuss the advantages and disadvantages of the key aspects of this method,including sample preparation and method validation.Finally,we outline the challenges and prospects of such methods in practical applications.
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作者姓名:
Yu Han;Xi-Ling Li;Minghui Zhang;Jing Wang;Su Zeng;Jun Zhe Min
作者机构:
Key Laboratory of Natural Medicines of the Changbai Mountain,Ministry of Education,Department of Pharmaceutical Analysis,College of Pharmacy,Yanbian University,Yanji,Jilin,133002,China;Institute of Drug Metabolism and Pharmaceutical Analysis,Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China
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引用格式:
[1]Yu Han;Xi-Ling Li;Minghui Zhang;Jing Wang;Su Zeng;Jun Zhe Min-.Potential use of a dried saliva spot(DSS)in therapeutic drug monitoring and disease diagnosis)[J].药物分析学报(英文),2022(06):815-823
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AB值:
0.516003
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