典型文献
Exercise"CALM"and make CAR-T therapy work better
文献摘要：
Chimeric antigen receptor(CAR)-T therapy was first described in 1989 and has revolutionized the management of hematological cancers with its great potential in reinforcing T cells against tumors[1].CAR-T therapies are mechanistically different from more tradi-tional approaches to the treatment of hematological cancers such as surgery,chemorad iotherapy,and monoclonal antibody therapy.To date,six CAR-T products have been approved by the US Food and Drug Administration(FDA)and successfully applied to the treatment of B-cell acute lymphoblastic leukemia(B-ALL),diffuse large B cell lymphoma(DLBCL),follicular lymphoma(FL),and mul-tiple myeloma(MM).Whilst there has been progress in the identi-fication of new targets and related technologies for solid tumors,commercial products are not yet available.
文献关键词：
中图分类号：
作者姓名：
Heng Mei;Parameswaran Hari;Yu Hu
作者机构：
Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Division of Hematology/Oncology,Medical College of Wisconsin,Milwaukee 53226,USA
文献出处：
引用格式：
[1]Heng Mei;Parameswaran Hari;Yu Hu-.Exercise"CALM"and make CAR-T therapy work better)[J].科学通报（英文版）,2022(19):1925-1928
A类：
chemorad,iotherapy
B类：
Exercise,CALM,make,CAR,work,better,Chimeric,antigen,receptor,was,first,described,has,revolutionized,management,hematological,cancers,its,great,potential,reinforcing,cells,against,tumors,therapies,are,mechanistically,different,from,more,tradi,tional,approaches,treatment,such,surgery,monoclonal,antibody,To,date,six,products,have,been,approved,by,US,Food,Drug,Administration,FDA,successfully,applied,acute,lymphoblastic,leukemia,ALL,diffuse,large,lymphoma,DLBCL,follicular,FL,mul,tiple,myeloma,MM,Whilst,there,progress,identi,fication,new,targets,related,technologies,solid,commercial,not,yet,available
AB值：
0.733956
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