典型文献
Light-field micro-endoscopy using a fiber bundle: a snapshot 3D epi-fluorescence endoscope
文献摘要：
Micro-endoscopes are widely used for detecting and visualizing hard-to-reach areas of the human body and for in vivo observation of animals. A micro-endoscope that can realize 3D imaging at the camera framerate could benefit various clinical and biological applications. In this work, we report the development of a compact light-field micro-endoscope (LFME) that can obtain snapshot 3D fluorescence imaging, by jointly using a single-mode fiber bundle and a small-size light-field configuration. To demonstrate the real imaging performance of our method, we put a resolution chart in different z positions and capture the z-stack images successively for reconstruction, achieving 333-μm-diameter field of view, 24 μm optimal depth of field, and up to 3.91 μm spatial resolution near the focal plane. We also test our method on a human skin tissue section and HeLa cells. Our LFME prototype provides epi-fluorescence imaging ability with a relatively small (2-mm-diameter) imaging probe, making it suitable for in vivo detection of brain activity and gastrointestinal diseases of animals.
文献关键词：
中图分类号：
作者姓名：
You Zhou;Bo Xiong;Weizhi Song;Xu Zhang;Guoan Zheng;Qionghai Dai;Xun Cao
作者机构：
School of Electronic Science and Engineering, Nanjing University, Nanjing 210023, China;Department of Automation, Tsinghua University, Beijing 100084, China;Institute for Brain and Cognitive Sciences, Tsinghua University, Beijing 100084, China;Beijing Institute of Collaborative Innovation, Beijing 100094, China;Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut 06269, USA;e-mail: qhdai@mail.tsinghua.edu.cn;e-mail: caoxun@nju.edu.cn
文献出处：
引用格式：
[1]You Zhou;Bo Xiong;Weizhi Song;Xu Zhang;Guoan Zheng;Qionghai Dai;Xun Cao-.Light-field micro-endoscopy using a fiber bundle: a snapshot 3D epi-fluorescence endoscope)[J].光子学研究（英文）,2022(09):2247
A类：
framerate,LFME
B类：
Light,field,micro,endoscopy,using,fiber,bundle,snapshot,epi,fluorescence,Micro,endoscopes,widely,used,detecting,visualizing,hard,reach,areas,human,body,vivo,observation,animals,that,can,realize,imaging,camera,could,benefit,various,clinical,biological,applications,In,this,work,we,report,development,compact,light,obtain,by,jointly,single,mode,small,size,configuration,To,demonstrate,performance,our,method,put,resolution,chart,different,positions,capture,stack,images,successively,reconstruction,achieving,diameter,view,optimal,depth,up,spatial,near,focal,plane,We,also,skin,tissue,section,HeLa,cells,Our,prototype,provides,ability,relatively,probe,making,suitable,detection,brain,activity,gastrointestinal,diseases
AB值：
0.6199
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
