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典型文献
A label-free lateral offset spliced coreless fiber MZI bio-sensor based on hydrophobin HGFI for TNF-α detec-tion
文献摘要:
A real-time label-free lateral offset spliced coreless fiber(CF)Mach-Zehnder interferometer(MZI)biosensor func-tionalized with hydrophobin Grifola frondosa I(HGFI)was proposed for the detection of cytokine tumour necrosis factor alpha(TNF-α).The nanolayer self-assembled on the optical fiber surfaces by HGFI rendered the immobilization of probe TNF-α antibody and recognition of antigen TNF-α.Trifluoroacetic acid was utilized to remove the HGFI layer from the glass surface,which was validated by field emission scanning electron microscopy(FESEM)and water contact angle(WCA).Results demonstrated that the processes of HGFI modification,antibody immobilization and specific antibody detection can be monitored in real time.The proposed biosensor exhibited good specificity,repeat-ability and low detection limit for TNF-α,extending its application in inflammation and disease monitoring.
文献关键词:
作者姓名:
WANG Bo;DUAN Shaoxiang;ZHANG Hao;XU Haijin;LIU Bo;QIAO Mingqiang
作者机构:
The Key Laboratory of Molecular Microbiology and Technology,Ministry of Education,Nankai University,Tianjin 300071,China;Institute of Modern Optics,Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology,Nankai University,Tianjin 300350,China;School of Life Science,Shanxi University,Taiyuan 030006,China
引用格式:
[1]WANG Bo;DUAN Shaoxiang;ZHANG Hao;XU Haijin;LIU Bo;QIAO Mingqiang-.A label-free lateral offset spliced coreless fiber MZI bio-sensor based on hydrophobin HGFI for TNF-α detec-tion)[J].光电子快报(英文版),2022(05):263-268
A类:
hydrophobin,HGFI,Trifluoroacetic
B类:
label,free,lateral,offset,spliced,coreless,fiber,MZI,real,CF,Mach,Zehnder,interferometer,biosensor,func,tionalized,Grifola,frondosa,was,proposed,detection,cytokine,tumour,necrosis,alpha,nanolayer,self,assembled,optical,surfaces,by,rendered,immobilization,probe,antibody,recognition,antigen,acid,utilized,remove,from,glass,which,validated,field,emission,scanning,electron,microscopy,FESEM,water,contact,angle,WCA,Results,demonstrated,that,processes,modification,monitored,exhibited,good,specificity,repeat,ability,low,limit,extending,its,application,inflammation,disease,monitoring
AB值:
0.551491
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