Biosensors are a focus of research on terahertz metasurfaces.However,reports of ultra-sensitive biosensors based on Dirac points are rare.Here,a new terahertz metasurface is proposed that consists of patterned graphene and perovskites.This serves as an ultra-sensitive Dirac-point-based biosensor for qualitative detection of sericin.Theoretically,sericin may make graphene n-doped and drive the Fermi level to shift from the valence band to the Dirac point,causing a dramatic decrease in conductivity.Correspondingly,the dielectric environment on the metasurface undergoes significant change,which is suited for ultra-sensitive biosensing.In addition,metal halide perovskites,which are up-to-date optoelectronic materials,have a positive effect on the phase during terahertz wave transmission.Thus,this sensor was used to successfully detect sericin with a detection limit of 780 pg/mL,achieved by changing the amplitude and phase.The detection limit of this sensor is as much as one order of magnitude lower than that of sensors in published works.These results show that the Dirac-point-based biosensor is a promising platform for a wide range of ultra-sensitive and qualitative detection in biosensing and biological sciences.

XIN YAN;TENGTENG LI;GUOHONG MA;JU GAO;TONGLING WANG;HAIYUN YAO;MAOSHENG YANG;LANJU LIANG;JING LI;JIE LI;DEQUAN WEI;MENG WANG;YUNXIA YE;XIAOXIAN SONG;HAITING ZHANG;CHAO MA;YUNPENG REN;XUDONG REN;JIANQUAN YAO

School of Opto-electronic Engineering,Zaozhuang University,Zaozhuang 277160,China;College of Precision Instruments and Opto-electronics Engineering,Tianjin University,Tianjin 300072,China;Department of Physics,School of Science,Shanghai University,Shanghai 200444,China;School of Telecommunications,Qilu University of Technology,Jinan 250306,China;Institute of Micro-nano Optoelectronics and Terahertz Technology,College of Information Science and Engineering,Jiangsu University,Zhenjiang 212013,China

光子学研究（英文）

[1]XIN YAN;TENGTENG LI;GUOHONG MA;JU GAO;TONGLING WANG;HAIYUN YAO;MAOSHENG YANG;LANJU LIANG;JING LI;JIE LI;DEQUAN WEI;MENG WANG;YUNXIA YE;XIAOXIAN SONG;HAITING ZHANG;CHAO MA;YUNPENG REN;XUDONG REN;JIANQUAN YAO-.Ultra-sensitive Dirac-point-based biosensing on terahertz metasurfaces comprising patterned graphene and perovskites)[J].光子学研究（英文）,2022(02):280-288

sericin

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