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典型文献
Purifying chylous plasma by precluding triglyceride via carboxylated polyethersulfone microfiltration membrane
文献摘要:
Precluding the excessive lipoproteins from plasma rapidly and effectively is highly needed for biomedical detection and reducing plasma product scrap in blood donation stations.The current centrifugation pro-cedure is high-cost and time-consuming.Herein,we fabricated an anionic microfiltration polyethersul-fone(PES)membrane modified by interface swelling and implanting of acrylic acid(AA)for screening out large particle lipoprotein chylomicron(CM)and adsorbing cationic very low-density lipoproteins(VLDL).To improve the separation efficiency,a two-stage filtration through carboxylated polyethersul-fone microfiltration membranes with the mean pore size of 0.45 and 0.22 μm respectively were con-ducted.Attenuated total reflection Fourier transform infrared technique(ATR-FTIR),water contact angle(WCA),Zeta potential and scanning electron microscope(SEM)were employed to characterize the modified membrane.To test the effectiveness of this membrane,plasma flux and concentration vari-ation of plasma components were examined to study the purification effectiveness.Furthermore,the hemocompatibility of modified membranes was tested to confirm its practicability on blood-contacting materials.The carboxylated polyethersulfone microfiltration membrane shows its promising potential application to purify chylous plasma.
文献关键词:
作者姓名:
Yang Liu;Qiu Han;Guiliang Li;Haibo Lin;Fu Liu;Gang Deng;Dingfeng Lv;Weijie Sun
作者机构:
Ningbo Institute of Materials Technology&Engineering,Chinese Academy of Sciences,Ningbo 315000,China;University of Chinese Academy of Sciences,Beijing 100049,China;The Ningbo Central Blood Station,Ningbo 315099,China;Department of Blood Transfusion,Ningbo First Hospital,Ningbo 315010,China
引用格式:
[1]Yang Liu;Qiu Han;Guiliang Li;Haibo Lin;Fu Liu;Gang Deng;Dingfeng Lv;Weijie Sun-.Purifying chylous plasma by precluding triglyceride via carboxylated polyethersulfone microfiltration membrane)[J].中国化学工程学报(英文版),2022(09):130-139
A类:
Purifying,Precluding,polyethersul,fone,chylomicron
B类:
chylous,plasma,by,precluding,triglyceride,via,carboxylated,polyethersulfone,microfiltration,excessive,lipoproteins,from,rapidly,effectively,highly,needed,biomedical,detection,reducing,product,scrap,blood,donation,stations,current,centrifugation,cedure,cost,consuming,Herein,fabricated,anionic,PES,modified,interface,swelling,implanting,acrylic,acid,AA,screening,out,large,particle,CM,adsorbing,cationic,very,low,density,VLDL,To,improve,separation,efficiency,two,stage,through,membranes,mean,pore,size,respectively,were,ducted,Attenuated,total,reflection,Fourier,transform,infrared,technique,ATR,FTIR,water,angle,WCA,Zeta,potential,scanning,electron,microscope,employed,characterize,effectiveness,this,flux,concentration,vari,components,examined,study,purification,Furthermore,hemocompatibility,was,tested,confirm,its,practicability,contacting,materials,shows,promising,application,purify
AB值:
0.613119
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