典型文献
Tea as a natural gift for discovering antiviral candidates
文献摘要：
Coronavirus disease(COVID-19)remains rampant worldwide and poses a serious threat to human health.Tea is a medicinal and edible homologous plant that exhibits potential anti-SARS-CoV-2 properties via the prevention of virus entry into host cells,inhibition of virus replication,and enhancement of the innate and cellular immune responses.In this review,the properties of six major types of tea were systematically summarized,including green tea,yellow tea,white tea,oolong tea,black tea,and dark tea.We focused on the primary components of tea exhibiting antiviral activities,which included(-)-epigallocatechin-3-gallate,(-)-gallocatechin gallate,tannic acid,oolonghomobisflavan A,theaflavins,and white-tip silver needle flavonoids.Among them,(-)-epigallocatechin-3-gallate is proposed to be an antiviral compound that interferes with the entire life cycle of SARS-CoV-2 by balancing inflammation and immunity.Thus,this compound can serve as a promising lead structure for the development of SARS-CoV-2 inhibitors.
文献关键词：
中图分类号：
作者姓名：
Changjian Wang;Zhiying Yang;Xin Chai;Yuefei Wang;Weili Wang;Min Zhang
作者机构：
State Key Laboratory of Component-based Chinese Medicine,Tianjin Key Laboratory of TCM Chemistry and Analysis,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Haihe Laboratory of Modern Chinese Medicine,Tianjin,China;Bioentropy Therapeutics Inc.,Cambridge,MA,USA
文献出处：
引用格式：
[1]Changjian Wang;Zhiying Yang;Xin Chai;Yuefei Wang;Weili Wang;Min Zhang-.Tea as a natural gift for discovering antiviral candidates)[J].针灸和草药（英文）,2022(04):211-220
A类：
oolonghomobisflavan
B类：
Tea,natural,gift,discovering,antiviral,candidates,Coronavirus,disease,remains,rampant,worldwide,poses,serious,threat,human,health,medicinal,edible,homologous,plant,that,exhibits,potential,SARS,CoV,properties,via,prevention,entry,into,host,cells,inhibition,replication,enhancement,innate,cellular,immune,responses,In,this,review,six,major,types,tea,were,systematically,summarized,including,green,yellow,white,black,dark,We,focused,primary,components,exhibiting,activities,which,included,epigallocatechin,gallate,tannic,acid,theaflavins,tip,silver,needle,flavonoids,Among,them,proposed,be,compound,interferes,entire,life,cycle,by,balancing,inflammation,immunity,Thus,serve,promising,lead,structure,development,inhibitors
AB值：
0.657649
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
