Natalie Yan?Lin Pang;Alexander Shao?Rong Pang;Vincent T.Chow;De?Yun Wang-Yong Loo Lin School of Medicine, National University of Singapore,Singapore 119228, Singapore;Department of Microbiology and Immunology, National University of Singapore, Science Drive 2,Singapore 117545, Singapore;Infectious Diseases Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore;Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore

Xue?Liang Peng;Ji?Si?Yu Cheng;Hai?Lun Gong;Meng?Di Yuan;Xiao?Hong Zhao;Zibiao Li;Dai?Xu Wei-Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Department of Life Sciences and Medicine, Northwest University, Xi'an 710069, China;Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis,#08-03, Singapore 138634, Singapore

Madeline Borel;Luyu Xie;Olivia Kapera;Adrian Mihalcea;Jeffrey Kahn;Sarah E.Messiah-School of Public Health,University of Texas Health Science Center,Dallas Campus,2777 N Stemmons Fwy,Dallas,TX 75207,USA;Center for Pediatric Population Health,University of Texas Health School of Public Health and Children's Health System of Texas,Dallas,TX,USA;School of Public Health,University of Texas Health Science Center,Austin Campus,Austin,TX,USA;School of Public Health,University of Texas Health Science Center,Houston Campus,Houston,TX,USA;Department of Pediatrics,University of Texas Southwestern Medical Center,Dallas,TX,USA;Children's Health System of Texas,Dallas,TX,USA

Carolina Valderas;Gastón Méndez;Alejandra Echeverría;Nelson Suarez;Katherin Julio;Francisca Sandoval-Department of Neurology,Hospital Dr.Exequiel González Cortés,Gran Avenida José Miguel Carrera 3300,8900085 Santiago,Región Metropolitana,Chile

Shalini Nair;Xinguang Chen-Department of Epidemiology,University of Florida,2004 Mowry Road,Gainesville,Florida,32610,USA

Elliot Mbunge;John Batani;Goabaone Gaobotse;Benhildah Muchemwa-Department of Computer Science,Faculty of Science and Engineering,University of Eswatini,Kwaluseni,Manzini,Eswatini;Department of Information Technology,Faculty of Accounting and Informatics,Durban University of Technology,South Africa;Faculty of Engineering and Technology,Botho University,Lesotho;Department of Biological Sciences and Biotechnology,Faculty of Science,Botswana International University of Science and Technology,Botswana

He Junyi;Guo Zhaoyu;Yang Pin;Cao Chunli;Xu Jing;Zhou Xiaonong;Li Shizhu-National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China;School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Zheng Jin-Xin;Lv Shan;Tian Li-Guang;Guo Zhao-Yu;Zheng Pei-Yong;Chen Yue-Lai;Guan Shi-Yang;Wang Wei-Ming;Zhang Shun-Xian-Department of Nephrology, Ruijin Hospital, Institute of Nephrology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People’s Republic of China;Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, National Institute of Parasitic Diseases, Shanghai 200025, People’s Republic of China;Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, People’s Republic of China;Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, People’s Republic of China;School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, People’s Republic of China;One Health Center, Shanghai Jiao Tong University–The University of Edinburgh, Shanghai 200025, People’s Republic of China

Jing Hong;Xiao-wan Xu;Jing Yang;Jing Zheng;Shu-mei Dai;Ju Zhou;Qing-mei Zhang;Yi Ruan;Chang-quan Ling-School of Traditional Chinese Medicine,Naval Medical University,Shanghai 200433,China;Department of Integrative Oncology,Changhai Hospital,Naval Medical University,Shanghai 200433,China;Department of Oncology,The First Affiliated Hospital,Bengbu Medical College,Bengbu 233010,Anhui Province,China;Department of Nursing,Fuyang Cancer Hospital,Fuyang 236000,Anhui Province,China;Department of Cardiac Rehabilitation,Shanghai First Rehabilitation Hospital,Shanghai 200090,China;Department of Radiation Oncology,Anhui Chest Hospital,Hefei 230022,Anhui Province,China;Department of Anesthesiology,Chaohu Hospital,Anhui Medical University,Hefei 238000,Anhui Province,China

Witoo Dilokthornsakul;Ramanya Kosiyaporn;Rattanamanee Wuttipongwaragon;Piyameth Dilokthornsakul-Center of Pharmaceutical Outcomes Research,Department of Pharmacy Practice,Faculty of Pharmaceutical Sciences,Naresuan University,Mueang,Phitsanulok 65000,Thailand

Keat Lam Ho;Phaik Har Yong;Chee Woon Wang;Umah Rani Kuppusamy;Chek Tung Ngo;Festo Massawe;Zhi Xiang Ng-School of Biosciences,Faculty of Science and Engineering,University of Nottingham Malaysia,43500 Selangor,Malaysia;School of Bioscience,Faculty of Medicine,Bioscience and Nursing,MAHSA University,42610 Selangor,Malaysia;Department of Biochemistry,Faculty of Medicine,Bioscience and Nursing,MAHSA University,42610 Selangor,Malaysia;Department of Biomedical Science,Faculty of Medicine,University of Malaya,50603 Kuala Lumpur,Malaysia;Optimax Sunway Eye Specialist Centre,Bandar Sunway,46150 Selangor,Malaysia

Han Yongyue;Pan Juanli;Ma Yanhong;Zhou Dongfang;Xu Wei-Department of Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China;Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China;Research Center of Medical and Pharmaceutical Bioengineering, Ministry of Health. Daan Gene Co., Ltd, Guangzhou 510665, China

Falah Hasan Obayes AL-Khikani;Aalae Salman Ayit-Medical Technique Department,College of Medical Technique,The Islamic University,Babylon,Iraq

Fengwen Yang;Bo Pang;Xinyao Jin;Zhe Chen;Wentai Pang;Qingquan Liu;Junhua Zhang;Boli Zhang-State Key Laboratory of Component-Based Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Haihe Laboratory of Modern Chinese Medicine,Tianjin,China;Beijing Hospital of Traditional Chinese Medicine,Beijing,China

Meng Xia;Bo Pang;Shaowei Yi;Xinjue Shan;Shizhe Deng;Yinan Qin;Tao Jiang;Hai Lu-Alberta College of Acupuncture&Traditional Chinese Medicine,Alberta,Canada;Evidence-based Medicine Center,TianjinUniversity of Traditional Chinese Medicine,Tianjin,China;School of Acupuncture-moxibustion and Tuina,Tianjin University of Traditional Chinese Medicine,Tianjin,China;School of Traditional ChineseMedicine,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Department of Acupuncture and Moxibustion,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin,China;School of Acupuncture-moxibustion and Tuina,Shaanxi University of Chinese Medicine,Xianyang,China;Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School,Nanjing,China

Xuan Li;Nuttapong Wichai;Jiabao Wang;Xiuping Liu;Huimin Yan;Yu Wang;Mingchi Luo;Shengyuan Zhou;Kai Wang;Lin Li;Lin Miao-State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Institute of Traditional Chinese Medicine,Tianjin University ofTraditional Chinese Medicine,Tianjin,China;Faculty of Pharmacy,Mahasarakham University,Mahasarakham,Thailand;Institute of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae,Ministry of Education,Tianjin University of Traditional Chinese Medicine,Tianjin,China;Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin,China

Jia Lu;Qiangling Yin;Rongjuan Pei;Qiu Zhang;Yuanyuan Qu;Yongbing Pan;Lina Sun;Ding Gao;Cuiqin Liang;Jingwen Yang;Wei Wu;Jiandong Li;Zongqiang Cui;Zejun Wang;Xinguo Li;Dexin Li;Shiwen Wang;Kai Duan;Wuxiang Guan;Mifang Lian;Xiaoming Yang-National Engineering Technology Research Center for Combined Vaccines,Wuhan Institute of Biological Products Co.Ltd.,Wuhan,430070,China;State Key Laboratory for Molecular Virology and Genetic Engineering National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing,102206,China;Center for Emerging Infectious Diseases,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,430071,China;CDC-WIV Joint Research Center for Emerging Diseases and Biosafety,Wuhan,430071,China;Institution of Infectious Diseases,Shenzhen Bay Laboratory,Shenzhen,518107,China

Danrong Shi;Keda Chen;Xiangyun Lu;Linfang Cheng;Tianhao Weng;Fumin Liu;Nanping Wu;Lanjuan Li;Hangping Yao-State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,National Medical Center for Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,310003,China;Shulan International Medical College,Zhejiang Shuren University,Hangzhou,310015,China

Hang Yang;Huijun Yuan;Xiaohui Zhao;Meng Xun;Shangrui Guo;Nan Wang;Bing Liu;Hongliang Wang-Department of Pathogen Biology and Immunology,School of Basic Medical Sciences,Xi'an Jiaotong University Health Science Center,Xi'an,710061,China;School of Pharmacy,Xi'an Jiaotong University Health Science Center,Xi'an,710061,China;BioBank,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China;Department of Life Sciences,Faculty of Natural Sciences,Imperial College London,London,SW7 2AZ,United Kingdom;Key Laboratory of Environment and Genes Related to Diseases,Xi'an Jiaotong University,Xi'an,710061,China

Qizan Gong;Changle Wang;Xia Chuai;Sandra Chiu-Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,230026,China;Department of Pathogenic Biology,Hebei Medical University,Shijiazhuang,Hebei,050017,China