首站-论文投稿智能助手
典型文献
Monkeypox virus:a re-emergent threat to humans
文献摘要:
Human monkeypox(MPX)is a rare zoonotic infection characterized by smallpox-like signs and symptoms.It is caused by monkeypox virus(MPXV),a double stranded DNA virus belonging to the genus Orthopoxvirus.MPX was first identified in 1970 and mostly prevailed in the rural rainforests of Central and West Africa in the past.Outside Africa,MPX was reported in the United Kingdom,the USA,Israel,and Singapore.In 2022,the resurgence of MPX in Europe and elsewhere posed a potential threat to humans.MPXV was transmitted by the animals-human or human-human pathway,and the symptoms of MPXV infection are similar to that of smallpox,but in a milder form and with lower mortality(1%-10%).Although the smallpox vaccination has been shown to provide 85%pro-tection against MPXV infection,and two anti-smallpox virus drugs have been approved to treat MPXV,there are still no specific vaccines and drugs against MPXV infection.Therefore it is urgent to take active measures including the adoption of novel anti-MPXV strategies to control the spread of MPXV and prevent MPX epidemic.In this review,we summarize the biological features,epidemiology,pathogenicity,laboratory diagnosis,and prevention and treatment strategies on MPXV.This review provides the basic knowledge for prevention and control of future outbreaks of this emerging infection.
文献关键词:
作者姓名:
Qizan Gong;Changle Wang;Xia Chuai;Sandra Chiu
作者机构:
Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,230026,China;Department of Pathogenic Biology,Hebei Medical University,Shijiazhuang,Hebei,050017,China
文献出处:
引用格式:
[1]Qizan Gong;Changle Wang;Xia Chuai;Sandra Chiu-.Monkeypox virus:a re-emergent threat to humans)[J].中国病毒学,2022(04):477-482
A类:
B类:
Monkeypox,emergent,threat,humans,Human,monkeypox,rare,zoonotic,infection,characterized,by,smallpox,like,signs,symptoms,It,caused,MPXV,double,stranded,belonging,genus,Orthopoxvirus,was,first,identified,mostly,prevailed,rural,rainforests,Central,West,Africa,past,Outside,reported,United,Kingdom,USA,Israel,Singapore,In,resurgence,Europe,elsewhere,posed,potential,transmitted,animals,pathway,similar,that,but,milder,form,lower,mortality,Although,vaccination,has,been,shown,tection,against,two,anti,drugs,have,approved,there,still,specific,vaccines,Therefore,urgent,take,active,measures,including,adoption,novel,strategies,control,spread,epidemic,this,review,summarize,biological,features,epidemiology,pathogenicity,laboratory,diagnosis,prevention,treatment,This,provides,basic,knowledge,future,outbreaks,emerging
AB值:
0.561736
相似文献
A broadly neutralizing human monoclonal antibody against the hemagglutinin of avian influenza virus H7N9
Li Jingxin;Zhang Li;Bao Linlin;Wang Yuxiao;Qiu Lin;Hu Jialei;Tang Rong;Yu Huiyan;Shan Jun;Li Yan;Qin Chuan;Zhu Fengcai-Department for Vaccine Clinical Evaluation, NHC Key Laboratory of Enteric Pathogenic Microbiology, Jlangsu Provincial Center for Diseases Control and Prevention, Nanjing, Jiangsu 210009, China;Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) & Comparative Medicine Center, Peking Union Medical Collage (PUMC); Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases, Beijing 100101, China;Department of Public Health, Southeast University, Nanjing, Jiangsu 210009, China;Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Low rate of pre-exposure prophylaxis and post-exposure prophylaxis uptake and high prevalence of transmitted drug resistance among newly diagnosed primary HIV infections in Shenzhen, China: a real-world retrospective study
Peng Qiaoli;Liu Xiaoning;Tang Xian;Zhang Qiuyue;Zhao Jin;Zheng Chenli;Zhao Fang;Zhou Yang;Zhang Lukun;Sun Liqin;Zhang Haitao;Jia Xinyun;Song Ying;Cao Tingzhi;Wang Siyuan;Rao Man;Chen Zhiwei;Wang Hui;He Yun-National Clinical Research Center for Infectious Diseases, HKU AIDS Institute Shenzhen Research Laboratory, The Third People’s Hospital of Shenzhen and The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong 518112, China;National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom;Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong 518073, China;Department of Microbiology, AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China
Evidence of SARS-CoV-2 infection in pets, captive non-human primates and farm animals in Central Africa
Gael D.Maganga;Barthélémy Ngoubangoye;Jumafra P.Koumba;Sonia Lekana-Douki;Ivan C.Moussadji Kinga;Thierry A.Tsoumbou;Antoine M.Mbeang Beyeme;Telstar G.Ndong Mebaley;Jean-Bernard Lekana-Douki-Centre Interdisciplinaire de Recherches Médicales de Franceville(CIRMF),UnitéEmergence des Maladies Virales,BP 769,Franceville,Gabon;Institut National Supérieur d'Agronomie et de Biotechnologies(INSAB),Universitédes Sciences et Techniques de Masuku(USTM),BP 941,Franceville,Gabon;Universitéde Lyon,Université Lyon 1,CNRS,Laboratoire de Biométrie et Biologieévolutive UMR 5558,69622 Villeurbanne,France;LabEx ECOFECT,Eco-evolutionary Dynamics of Infectious Diseases,University of Lyon,Lyon,France
Therapeutic potential of traditional Chinese medicine for the treatment of NAFLD:A promising drug Potentilla discolor Bunge
Longshan Ji;Qian Li;Yong He;Xin Zhang;Zhenhua Zhou;Yating Gao;Miao Fang;Zhuo Yu;Robim M.Rodrigues;Yueqiu Gao;Man Li-Laboratory of Cellular Immunity,Institute of Clinical Immunology,Shanghai Key Laboratory of Traditional Chinese Medicine,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Key Laboratory of Liver and Kidney Diseases(Shanghai University of Traditional Chinese Medicine),Ministry of Education,Shanghai 201203,China;Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Department of Hepatopathy,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of in Vitro Toxicology and Dermato-Cosmetology,Faculty of Medicine and Pharmacy,Vrije Universiteit Brussel,Brussels 1000,Belgium
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
Ying Dong;Bi-xi Tang;Qi Wang;Li-wei Zhou;Cong Li;Xuan Zhang;Dan-dan Sun;Xin Sun;Xue-mei Zhang;Bing Xiong;Jia Li;Hong Shi;Dan-qi Chen;Yi Zang-State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;Department of Pharmacology,School of Pharmacy,Fudan University,Shanghai 201203,China;Department of Medicinal Chemistry,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Center for Supramolecular Chemistry and Catalysis and Department of Chemistry,College of Sciences,Shanghai University,Shanghai 200444,China;Schoolof Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210023,China;Schoolof Pharmacy,Henan University,Kaifeng 475004,China;Open Studio for Druggability Research of Marine Natural Products,Pilot National Laboratory for Marine Science and Technology(Qingdao),Qingdao 266237,China;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,UCAS,Hangzhou 310024,China;Department of Anesthesiology of Shanghai Pulmonary Hospital,School of medicine,Tongji University,Shanghai 200433,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。