典型文献
1O2-activatable Eu3+-afterglow nanoprobe for highly sensitive detection of porphyria in whole blood
文献摘要：
High-sensitivity detection of porphyrin in blood is very important for the early diagnosis and treatment of porphyria. Based on the advantages of longer luminescence lifetime and lower background interfer-ence, organic afterglow molecular porphyrin detection probes were developed, but these probes show poor water solubility and insufficient luminescence intensity. Herein, we present an afterglow nanoprobe (Eu-NP) for porphyria detection in whole blood. The luminescent substance (europium complex) and the organic vinyl compound reacted with singlet oxygen (1O2) were selected for encapsulation in polystyrene spheres. Eu-NP can respond to 1O2 produced by porphyrins, and the detection signals can be obtained by the emission of the afterglow Eu3+-emissive nanosensor. Eu-NP can achieve high-sensitivity detection of porphyrin, and the lowest detection limit reaches 0.29μmol/L. The porphyrin detection in whole blood samples is consistent with clinical diagnosis results. Compared with the organic afterglow molecule, the Eu-NPs constructed in this work show a higher signal-to-noise ratio and sensitivity of porphyria detection.
文献关键词：
中图分类号：
作者姓名：
Jia Liu;Jiamiao Yin;Hang Yuan;Yiyang Zhao;Shihua Luo;Fuyou Li
作者机构：
Department of Chemistry,State Key Laboratory of Molecular Engineering of Polymers,Fudan University,Shanghai 200433,China;Hangzhou Foreign Languages School,Hangzhou 310023,China;Department of Traumatology,Ruijin Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200025,China
文献出处：
引用格式：
[1]Jia Liu;Jiamiao Yin;Hang Yuan;Yiyang Zhao;Shihua Luo;Fuyou Li-.1O2-activatable Eu3+-afterglow nanoprobe for highly sensitive detection of porphyria in whole blood)[J].稀土学报（英文版）,2022(09):1382-1388
A类：
B类：
1O2,activatable,Eu3+,afterglow,nanoprobe,highly,sensitive,detection,porphyria,whole,blood,High,sensitivity,very,important,early,diagnosis,treatment,Based,advantages,longer,luminescence,lifetime,lower,background,interfer,organic,molecular,probes,were,developed,but,these,show,poor,water,solubility,insufficient,intensity,Herein,present,luminescent,substance,europium,complex,vinyl,compound,reacted,singlet,oxygen,selected,encapsulation,polystyrene,spheres,can,respond,produced,by,porphyrins,signals,obtained,emission,emissive,nanosensor,achieve,lowest,limit,reaches,samples,consistent,clinical,results,Compared,molecule,NPs,constructed,this,work,higher,noise,ratio
AB值：
0.52653
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