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典型文献
Novel photoelectrochemical immunosensor for MCF-7 cell detection based on n-p organic semiconductor heterojunction
文献摘要:
In this work,we developed a novel photoelectrochemical(PEC)sensor based on n-p organic semicon-ductor heterojunction for sensitive detecting MCF-7 cancer cells.BTA-C4Ph and PM6 were designed as photoactive materials to form n-p heterojunction,which greatly enhanced the photoelectric conversion efficiency.Antibody-modified magnetic nanoparticles were utilized to capture and separate MCF-7 cells from samples.Detection of MCF-7 is ascribed to the loading of MCF-7 onto BTA-C4Ph-PM6 modified elec-trode that resulted in the decrease of photocurrent intensity.The PEC immunosensor displayed a linear concentration ranging from 50 cell/mL to 1×104 cell/mL with a limit of detection(LOD)of 41 cell/mL(S/N=3)for MCF-7.Additionally,the senor also exhibited good stability,excellent selectivity and promi-nent reproducibility.Furthermore,the sensor was successfully applied to detect MCF-7 in whole blood.This work illustrates that n-p heterojunction of organic semiconductor may find wide applications for the preparation of different photoelectrochemical sensors.
文献关键词:
作者姓名:
Qin Zeng;Qingya Wei;Jiarong Luo;Yong Qian;Minghui Yang;Yingping Zou;Limin Lu
作者机构:
Hunan Provincial Key Laboratory of Micro&Nano Materials Interface Science,College of Chemistry and Chemical Engineering,Central South University,Changsha 410083,China;Institute of Functional Materials and Agricultural Applied Chemistry,College of Science,Jiangxi Agricultural University,Nanchang 330045,China;Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation,East China University of Technology,Nanchang 330013,China
引用格式:
[1]Qin Zeng;Qingya Wei;Jiarong Luo;Yong Qian;Minghui Yang;Yingping Zou;Limin Lu-.Novel photoelectrochemical immunosensor for MCF-7 cell detection based on n-p organic semiconductor heterojunction)[J].中国化学快报(英文版),2022(06):2954-2958
A类:
C4Ph,senor
B类:
Novel,photoelectrochemical,immunosensor,MCF,detection,organic,semiconductor,heterojunction,In,this,work,developed,novel,PEC,sensitive,detecting,cancer,cells,BTA,PM6,were,designed,photoactive,materials,form,which,greatly,enhanced,photoelectric,conversion,efficiency,Antibody,modified,magnetic,nanoparticles,utilized,capture,separate,from,samples,Detection,ascribed,loading,onto,trode,that,resulted,decrease,photocurrent,intensity,displayed,linear,concentration,ranging,limit,LOD,Additionally,also,exhibited,good,stability,excellent,selectivity,promi,nent,reproducibility,Furthermore,was,successfully,applied,whole,blood,This,illustrates,may,find,wide,applications,preparation,different,sensors
AB值:
0.573264
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