典型文献
Ciprofloxacin stress changes key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4
文献摘要：
Ciprofloxacin(CIP)is an antibiotic used to treat infections caused by bacteria.In this experiment,key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4 was researched under CIP stress.The results showed that the activities of hexokinase,pyruvate kinase,-galactosidase and Na+,K+-ATPase after 1/2 minimum bacteriostatic concentration(MIC)CIP treatment were significantly decreased(P＜0.01).Gas chromatography-mass spectrometry was used to analysis the changes of main metabolites in the cells and principal component analysis and partial least square model were constructed.The results indicated that CIP could cause changes in intracellular fatty acids,carbohydrates and amino acids,and the mechanism of amino acid metabolism under CIP stress was significantly inhibited.L.plantarum DNZ-4 made stress response to CIP by regulating the ratio of saturated fatty acids and unsaturated fats.This experiment revealed the changes of growth and metabolism mechanism of L.plantarum DNZ-4 under CIP stress,which help to provide technical means for the development of effective probiotics preparation products.
文献关键词：
中图分类号：
作者姓名：
Pin Chen;Xiaoqian Chen;Wei Yu;Bo Zhou;Lihua Liu;Yuzhuo Yang;Peng Du;Libo Liu;Chun Li
作者机构：
Key Laboratory of Dairy Science,Ministry of Education,Food Science College,Northeast Agricultural University,Harbin 150030,China;Institute of Animal Science(IAS),Chinese Academy of Agricultural Sciences(CAAS),Beijing 100193,China;National Dairy Product Quality Supervision and Inspection Center,Harbin 150024,China
文献出处：
引用格式：
[1]Pin Chen;Xiaoqian Chen;Wei Yu;Bo Zhou;Lihua Liu;Yuzhuo Yang;Peng Du;Libo Liu;Chun Li-.Ciprofloxacin stress changes key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4)[J].食品科学与人类健康（英文）,2022(02):332-340
A类：
DNZ
B类：
Ciprofloxacin,stress,changes,key,enzymes,intracellular,metabolites,Lactobacillus,plantarum,CIP,antibiotic,infections,caused,by,bacteria,In,this,experiment,was,researched,under,results,showed,that,activities,hexokinase,pyruvate,galactosidase,Na+,K+,ATPase,after,minimum,bacteriostatic,concentration,MIC,treatment,were,significantly,decreased,Gas,chromatography,mass,spectrometry,analysis,main,cells,principal,component,partial,least,square,model,constructed,indicated,could,fatty,acids,carbohydrates,amino,mechanism,metabolism,inhibited,made,response,regulating,unsaturated,fats,This,revealed,growth,which,help,provide,technical,means,development,effective,probiotics,preparation,products
AB值：
0.523393
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
