典型文献
Neuronal and endothelial transglutaminase-2 expression in experimental autoimmune encephalomyelitis and multiple sclerosis
文献摘要：
Multiple sclerosis (MS) is a neurological condition characterized by the disruption of the blood-brain barrier, immune system activation, and inflammation that is accompanied by glial reactivity, neuronal cell death, axon demyelination, and axotomy. Pathological changes result in functional loss including paralysis, migraine, vision problems, spasticity, and neuropathic pain. Although the causative factor responsible for triggering MS remains to be identified, anti-inflammatory treatments have been translated to clinical use with favorable reductions in the frequency, severity, and duration of relapses in the relapsing-remitting form of MS. Among the identified therapeutic targets in MS, transglutaminase-2 (TG2) has been reported to be involved in disease pathogenesis (Chrobok et al., 2018).
文献关键词：
中图分类号：
作者姓名：
Damien D.Pearse;Mousumi Ghosh
作者机构：
Miami Project to Cure Paralysis,University of Miami Miller School of Medicine,Miami,FL,USA;Department of Neurological Surgery,University of Miami Miller School of Medicine,Miami,FL,USA;Neuroscience Program,Interdisciplinary Stem Cell Institute,University of Miami Miller School of Medicine,Miami,FL,USA;Department of Veterans Affairs,Veterans Affairs Medical Center,Miami,FL,USA
文献出处：
引用格式：
[1]Damien D.Pearse;Mousumi Ghosh-.Neuronal and endothelial transglutaminase-2 expression in experimental autoimmune encephalomyelitis and multiple sclerosis)[J].中国神经再生研究（英文版）,2022(07):1471-1472
A类：
axotomy,Chrobok
B类：
Neuronal,endothelial,transglutaminase,expression,experimental,autoimmune,encephalomyelitis,multiple,sclerosis,Multiple,neurological,condition,characterized,by,disruption,blood,brain,barrier,system,activation,inflammation,that,accompanied,glial,reactivity,neuronal,cell,death,axon,demyelination,Pathological,changes,result,functional,loss,including,paralysis,migraine,vision,problems,spasticity,neuropathic,pain,Although,causative,responsible,triggering,remains,identified,anti,inflammatory,treatments,have,been,translated,clinical,use,favorable,reductions,frequency,severity,duration,relapses,relapsing,remitting,form,Among,therapeutic,targets,TG2,has,reported,involved,disease,pathogenesis
AB值：
0.738016
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
