典型文献
Aconitum heterophyllum Wall.ex Royle:A critically endangered medicinal herb with rich potential for use in medicine
文献摘要：
Aconitum heterophyllum(Patrees)is a critically endangered medicinal herb of the northwestern Himalayas and has enormous pharmacological potential.It is the only nonpoisonous member of the genus Aconitum,and has been used as a medicinal herb since ancient times.A.heterophyllum is an impor-tant ingredient in many traditional systems of medicine.Mostly,it is harvested for its roots,and its medicinal properties are due to the presence of diverse bioactive secondary metabolites,commonly known as aconites.Our understanding of the pharmacological properties of this intriguing genus is con-tinuously growing due to its broad chemical diversity.The therapeutic uses identified by traditional medicinal practice are receiving extensive study.Multiple in vitro experimental investigations of A.heterophyllum have reported the analgesic,anti-inflammatory,antiarrhythmic,antiparasitic and anti-cancer properties,as well as its effects on the central nervous system.In this review,we highlight the classification,distribution,commerce,traditional uses,phytochemistry,pharmacology and conservation measures relevant to this species.Additionally,this review includes the biosynthetic pathways of A.heterophyllum's key constituents,which could be targeted to enhance the expression levels of desired metabolites via genetic interventions.Studying the genomics,transcriptomics,proteomics and metabo-lomic aspects of this species would be helpful in developing highly designed genotypes and chemotypes of this species to be used in commercial production.
文献关键词：
中图分类号：
作者姓名：
Tareq A.Wani;Zahoor A.Kaloo;Nisar A.Dangroo
作者机构：
Plant Tissue Culture Laboratory,Department of Botany,University of Kashmir,Srinagar,Jammu and Kashmir 190006,India;Department of Chemistry,National Institute of Technology,Srinagar,Jammu and Kashmir 190006,India
文献出处：
引用格式：
[1]Tareq A.Wani;Zahoor A.Kaloo;Nisar A.Dangroo-.Aconitum heterophyllum Wall.ex Royle:A critically endangered medicinal herb with rich potential for use in medicine)[J].结合医学学报（英文版）,2022(02):104-113
A类：
heterophyllum,Patrees,nonpoisonous,aconites,tinuously,antiarrhythmic,antiparasitic,lomic
B类：
Aconitum,Wall,Royle,critically,endangered,medicinal,herb,rich,potential,medicine,northwestern,Himalayas,has,enormous,pharmacological,It,member,genus,been,used,since,ancient,times,impor,tant,ingredient,many,traditional,systems,Mostly,harvested,its,roots,properties,are,due,presence,diverse,bioactive,secondary,metabolites,commonly,known,Our,understanding,this,intriguing,growing,broad,chemical,diversity,therapeutic,uses,identified,by,practice,receiving,extensive,study,Multiple,vitro,experimental,investigations,have,reported,analgesic,inflammatory,cancer,well,effects,central,nervous,In,review,highlight,classification,distribution,commerce,phytochemistry,pharmacology,conservation,measures,relevant,species,Additionally,includes,biosynthetic,pathways,key,constituents,which,could,targeted,enhance,expression,levels,desired,via,genetic,interventions,Studying,genomics,transcriptomics,proteomics,aspects,would,helpful,developing,highly,designed,genotypes,chemotypes,commercial,production
AB值：
0.552244
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