典型文献
Roles of neutrophil reactive oxygen species (ROS) generation in organ function impairment in sepsis
文献摘要:
Sepsis is a condition of severe organ failure caused by the maladaptive response of the host to an infection. It is a severe complication affecting critically ill patients, which can progress to severe sepsis, septic shock, and ultimately death. As a vital part of the human innate immune system, neutrophils are essential in resisting pathogen invasion, infection, and immune surveillance. Neutrophil-produced reactive oxygen species (ROS) play a pivotal role in organ dysfunction related to sepsis. In recent years, ROS have received a lot of attention as a major cause of sepsis, which can progress to severe sepsis and septic shock. This paper reviews the existing knowledge on the production mechanism of neutrophil ROS in human organ function impairment because of sepsis.
文献关键词:
中图分类号:
作者姓名:
Jiaqi LU;Jingyuan LIU;Ang LI
作者机构:
Intensive Care Unit,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China
引用格式:
[1]Jiaqi LU;Jingyuan LIU;Ang LI-.Roles of neutrophil reactive oxygen species (ROS) generation in organ function impairment in sepsis)[J].浙江大学学报(英文版)(B辑:生物医学和生物技术),2022(06):437-450
A类:
maladaptive
B类:
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AB值:
0.575596
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