典型文献
Access to chiral homoallylic vicinal diols from carbonyl allylation of aldehydes with allyl ethers via palladium-catalyzed allylic C-H borylation
文献摘要：
Chiral homoallylic vicinal diols are found in many bioactive compounds and are among the most versatile functional groups in organic chemistry.Here,we describe an asymmetric carbonyl allylation of aldehydes with allyl ethers proceeding via allylic C-H borylation enabled by palladium and chiral phosphoric acid sequential catalysis,providing facile access to homoallylic vicinal anti-diols in high yields and with excellent stereoselectivity.This protocol enables the total synthesis of aigialomycin D to be finished within 7 steps.
文献关键词：
中图分类号：
作者姓名：
Tian-Ci Wang;Pu-Sheng Wang;Dian-Feng Chen;Liu-Zhu Gong
作者机构：
Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry,University of Science and Technology of China,Hefei 230026,China;Center for Excellence in Molecular Synthesis of CAS,Hefei 230026,China
文献出处：
引用格式：
[1]Tian-Ci Wang;Pu-Sheng Wang;Dian-Feng Chen;Liu-Zhu Gong-.Access to chiral homoallylic vicinal diols from carbonyl allylation of aldehydes with allyl ethers via palladium-catalyzed allylic C-H borylation)[J].中国科学:化学（英文版）,2022(02):298-303
A类：
homoallylic,borylation,aigialomycin
B类：
Access,chiral,vicinal,diols,from,carbonyl,allylation,aldehydes,ethers,via,palladium,catalyzed,Chiral,are,found,many,bioactive,compounds,among,most,versatile,functional,groups,organic,chemistry,Here,we,describe,asymmetric,proceeding,enabled,by,phosphoric,acid,sequential,catalysis,providing,facile,access,anti,high,yields,excellent,stereoselectivity,This,protocol,enables,total,synthesis,finished,within,steps
AB值：
0.552991
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