典型文献
Facile access to chiral 1-pyrrolines through Rh-catalyzed enantioselective partial hydrogenation of unprotected simple pyrroles
文献摘要：
Highly enantioselective Rh-catalyzed partial hydrogenation of unprotected simple 2-alkyl-5-aryl-disubstituted pyrroles has been successfully developed,generating a series of chiral 1-pyrroline deriva-tives generally with excellent results(95％-99％yields,91％-96％ee).Moreover,2,5-aryl-1H-pyrroles were hydrogenated well in high yields and good enantioselectivities.This efficient protocol features easily accessible substrates,wide substrate scope,well functional group compatibility,commercially available rhodium precursor and chiral ligand.It provides a versatile route to access chiral 1-pyrroline derivatives that are of great importance in organic synthesis and pharmaceutical chemistry.
文献关键词：
中图分类号：
作者姓名：
Kui Tian;Gongyi Liu;Xiu-Qin Dong
作者机构：
Engineering Research Centre of Organosilicon Compounds&Materials,Ministry of Education,College of Chemistry and Molecular Sciences,Wuhan University,Wuhan 430072,China;Suzhou Institute of Wuhan University,Suzhou 215123,China
文献出处：
引用格式：
[1]Kui Tian;Gongyi Liu;Xiu-Qin Dong-.Facile access to chiral 1-pyrrolines through Rh-catalyzed enantioselective partial hydrogenation of unprotected simple pyrroles)[J].中国化学快报（英文版）,2022(12):5092-5095
A类：
pyrrolines,pyrroles
B类：
Facile,chiral,through,Rh,catalyzed,enantioselective,partial,hydrogenation,unprotected,simple,Highly,alkyl,aryl,disubstituted,has,been,successfully,developed,generating,series,generally,excellent,results,yields,Moreover,1H,were,hydrogenated,well,high,good,enantioselectivities,This,efficient,protocol,features,easily,accessible,substrates,wide,scope,functional,group,compatibility,commercially,available,rhodium,precursor,ligand,It,provides,versatile,route,derivatives,that,are,great,importance,organic,synthesis,pharmaceutical,chemistry
AB值：
0.616893
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