典型文献
Anticancer drug screening of natural products: In vitro cytotoxicity assays, techniques, and challenges
文献摘要：
Natural products include several diverse compounds that have been found to be effective against cancer. Discovering anticancer compounds in nature is a multistep and complex process that requires pre-clinical and clinical studies. Only a few of the available natural products are used to treat cancer since most of them have very high complexity and low bioavailability. Therefore, the process of anticancer drug discovery requires a straightforward and effective method to assess anticancer activity using in vitro assays. This review summarizes various cell-based assays and techniques used to measure cell viability, migration, and apoptosis, focusing in particular on the principles, mechanisms, advantages, and disadvantages of each assay to provide a preliminary platform for cancer drug discovery.
文献关键词：
中图分类号：
作者姓名：
Agustina Setiawati;Damiana Sapta Candrasari;F.D.Erika Setyajati;Vincentia Krisnina Prasetyo;Dewi Setyaningsih;Yustina Sri Hartini
作者机构：
Faculty of Pharmacy,Sanata Dharma University,Paingan,Maguwoharjo,Depok,Sleman,Yogyakarta 55282,Indonesia
文献出处：
引用格式：
[1]Agustina Setiawati;Damiana Sapta Candrasari;F.D.Erika Setyajati;Vincentia Krisnina Prasetyo;Dewi Setyaningsih;Yustina Sri Hartini-.Anticancer drug screening of natural products: In vitro cytotoxicity assays, techniques, and challenges)[J].亚太热带生物医学杂志（英文版）,2022(07):279-289
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Anticancer,drug,screening,natural,products,In,vitro,cytotoxicity,assays,techniques,challenges,Natural,include,several,diverse,compounds,that,have,been,found,effective,against,Discovering,anticancer,nature,multistep,process,requires,clinical,studies,Only,few,available,are,used,treat,since,most,them,high,complexity,low,bioavailability,Therefore,discovery,straightforward,method,assess,activity,This,review,summarizes,various,cell,measure,viability,migration,apoptosis,focusing,particular,principles,mechanisms,disadvantages,each,provide,preliminary,platform
AB值：
0.617598
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