典型文献
The complement system and autoimmune diseases
文献摘要：
The complement system plays a key role in the pathogenesis of autoimmune diseases, which usually injures the kidney. More and more studies have shown the pathogenic role and indicated that abnormal activation of the complement system was highly involved in the outbreak of autoimmune diseases. This review mainly introduced recent studies of complement system activation contributing to the pathogenesis of autoimmune diseases, including systemic lupus erythematosus, antiphospholipid syndrome, antineutrophil cytoplasmic antibody-associated vasculitides, and so on. Understanding the pathogenic roles of complement activation in various autoimmune diseases will identify potential novel therapeutic targets on complement systems.
文献关键词：
ANCA-associated vasculitides;antiphospholipid syndrome;autoimmune disease;complement;systemic lupus erythematosus
中图分类号：
作者姓名：
Jia Changhao;Tan Ying;Zhao Minghui
作者机构：
Laboratory of Renal Disease, Department of Medicine, Renal Division, Ministry of Health of China, Peking University First Hospital, Peking University Institute of Nephrology, Beijing, China;Peking-Tsinghua Center for Life Sciences, Beijing, China;Center for Interdisciplinary Research in Biomedicine, Peking University, Beijing, China
文献出处：
引用格式：
[1]Jia Changhao;Tan Ying;Zhao Minghui-.The complement system and autoimmune diseases)[J].慢性疾病与转化医学（英文）,2022(03):184-190
A类：
injures,vasculitides
B类：
complement,autoimmune,diseases,plays,key,pathogenesis,which,usually,kidney,More,more,studies,have,shown,pathogenic,indicated,that,abnormal,activation,was,highly,involved,outbreak,This,review,mainly,introduced,recent,contributing,including,systemic,lupus,erythematosus,antiphospholipid,syndrome,antineutrophil,cytoplasmic,antibody,associated,Understanding,roles,various,will,identify,potential,novel,therapeutic,targets,systems,ANCA
AB值：
0.490632
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