典型文献
Recent advances in neutrophil chemotaxis abnormalities during sepsis
文献摘要：
Sepsis remains one of the leading causes of death globally, in spite of advanced developments in intensive care and better understandings of pathophysiology related to sepsis. There is no special treatment or drug available for sepsis, currently. Under normal circumstances, neutrophil is a major player in acute infection control. However, during sepsis, the migration abilities and antimicrobial functions of neutrophils are impaired, resulting in a dysregulated immune response. Recent studies have indeed demonstrated that blocking or reversing neutrophil migration and impaired antibacterial function can improve the outcomes in septic animal models. This article systemically synthesized information regarding related factors and signaling involved in the functions of neutrophils in sepsis. This review also discussed the possibility that neutrophils be used as a marker for specific diagnosis and/or prediction of the outcomes of sepsis.
文献关键词：
Sepsis;Neutrophil;Chemotaxis;Dysfunction;Migration
中图分类号：
作者姓名：
Zhou Yu-Ying;Sun Bing-Wei
作者机构：
Department of Burns and Plastic Surgery, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215002, Jiangsu Province, China
文献出处：
引用格式：
[1]Zhou Yu-Ying;Sun Bing-Wei-.Recent advances in neutrophil chemotaxis abnormalities during sepsis)[J].中华创伤杂志（英文版）,2022(06):317-324
A类：
B类：
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AB值：
0.67401
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