典型文献
The predictors of long-COVID in the cohort of Turkish Thoracic Society-TURCOVID multicenter registry: One year follow-up results
文献摘要:
Objective: To evaluate long-term effects of COVID-19, and to determine the risk factors in long-COVID in a cohort of the Turkish Thoracic Society (TTS)-TURCOVID multicenter registry.Methods: Thirteen centers participated with 831 patients; 504 patients were enrolled after exclusions. The study was designed in three-steps: (1) Phone questionnaire; (2) retrospective evaluation of the medical records; (3) face-to-face visit. Results: In the first step, 93.5% of the patients were hospitalized; 61.7% had a history of pneumonia at the time of diagnosis. A total of 27.1% reported clinical symptoms at the end of the first year. Dyspnea (17.00%), fatigue (6.30%), and weakness (5.00%) were the most prevalent long-term symptoms. The incidence of long-term symptoms was increased by 2.91 fold (95% CI 1.04-8.13, P=0.041) in the presence of chronic obstructive pulmonary disease and by 1.84 fold (95% CI 1.10-3.10, P=0.021) in the presence of pneumonia at initial diagnosis, 3.92 fold (95% CI 2.29-6.72, P=0.001) of dyspnea and 1.69 fold (95% CI 1.02-2.80, P=0.040) fatigue persists in the early-post-treatment period and 2.88 fold (95% CI 1.52-5.46, P=0.001) in the presence of emergency service admission in the post COVID period. In step 2, retrospective analysis of 231 patients revealed that 1.4% of the chest X-rays had not significantly improved at the end of the first year, while computed tomography (CT) scan detected fibrosis in 3.4%. In step 3, 138 (27.4%) patients admitted to face-to-face visit at the end of first year; at least one symptom persisted in 49.27% patients. The most common symptoms were dyspnea (27.60%), psychiatric symptoms (18.10%), and fatigue (17.40%). Thorax CT revealed fibrosis in 2.4% patients. Conclusions: COVID-19 symptoms can last for extended lengths of time, and severity of the disease as well as the presence of comorbidities might contribute to increased risk. Long-term clinical issues should be regularly evaluated after COVID-19.
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作者姓名:
Serap Argun Baris;Oya Baydar Toprak;Pelin Duru Cetinkaya;Fusun Fakili;Nurdan Kokturk;Seval Kul;Ozgecan Kayalar;Yildiz Tutuncu;Emel Azak;Mutlu Kuluozturk;Pinar Aysert Yildiz;Pelin Pinar Deniz;Oguz Kilinc;Ilknur Basyigit;Hasim Boyaci;Ismail Hanta;Neslihan Kose;Gulseren Sagcan;Caglar Cuhadaroglu;Hacer Kuzu Okur;Hasan Selcuk Ozger;Begum Ergan;Mehtap Hafizoglu;Abdullah Sayiner;Esra Nurlu Temel;Onder Ozturk;Tansu Ulukavak Ciftci;Ipek Kivilcim Oguzulgen;Vildan Avkan Oguz;Firat Bayraktar;Ozlem Ataoglu;Merve Ercelik;Pinar Yildiz Gulhan;Aysegul Tomruk Erdem;Muge Meltem Tor;Oya Itil;Hasan Bayram
作者机构:
Department of Pulmonary Medicine,Faculty of Medicine,Kocaeli University,Kocaeli,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Cukurova University,Adana,Turkey;Department of Pulmonary Medicine,University of Health Sciences,Adana City Training and Research Hospital,Adana,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Gaziantep University,Gaziantep,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Gazi University,Ankara,Turkey;Department of Biostatistics,Faculty of Medicine,Gaziantep University,Gaziantep,Turkey;Koc University Research Center for Translational Medicine(KUTTAM),Koc University School of Medicine,Istanbul,Turkey;Department of Immunology,Koc University Research Center for Translational Medicine(KUTTAM),Koc University School of Medicine,Istanbul,Turkey;Department of Infectious Disease and Clinical Microbiology,Faculty of Medicine,Kocaeli University,Kocaeli Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Firat University,Elazig,Turkey;Department of Infectious Diseases and Clinical Microbiology,Faculty of Medicine,Gazi University,Ankara,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Dokuz Eylul University,Izmir,Turkey;Department of Pulmonary Medicine,Bilecik Training and Research Hospital,Bilecik,Turkey;Department of Pulmonary Medicine,Altunizade Acibadem Hospital,Istanbul,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Ege University,Izmir,Turkey;Department of Infectious Diseases and Clinical Microbiology,Faculty of Medicine,Suleyman Demirel University,Isparta,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Suleyman Demirel University,Isparta,Turkey;Department of Infectious Disease and Clinical Microbiology,Faculty of Medicine,Dokuz Eylul University,Izmir,Turkey;Department of Internal Medicine,Faculty of Medicine,Dokuz Eylul University,Izmir,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Duzce University,Duzce,Turkey;Department of Pulmonary Medicine,Faculty of Medicine,Zonguldak Bulent Ecevit University,Zonguldak,Turkey;Department of Pulmonary Medicine,Koc University Research Center for Translational Medicine(KUTTAM),Koc University School of Medicine,Istanbul,Turkey
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引用格式:
[1]Serap Argun Baris;Oya Baydar Toprak;Pelin Duru Cetinkaya;Fusun Fakili;Nurdan Kokturk;Seval Kul;Ozgecan Kayalar;Yildiz Tutuncu;Emel Azak;Mutlu Kuluozturk;Pinar Aysert Yildiz;Pelin Pinar Deniz;Oguz Kilinc;Ilknur Basyigit;Hasim Boyaci;Ismail Hanta;Neslihan Kose;Gulseren Sagcan;Caglar Cuhadaroglu;Hacer Kuzu Okur;Hasan Selcuk Ozger;Begum Ergan;Mehtap Hafizoglu;Abdullah Sayiner;Esra Nurlu Temel;Onder Ozturk;Tansu Ulukavak Ciftci;Ipek Kivilcim Oguzulgen;Vildan Avkan Oguz;Firat Bayraktar;Ozlem Ataoglu;Merve Ercelik;Pinar Yildiz Gulhan;Aysegul Tomruk Erdem;Muge Meltem Tor;Oya Itil;Hasan Bayram-.The predictors of long-COVID in the cohort of Turkish Thoracic Society-TURCOVID multicenter registry: One year follow-up results)[J].亚太热带医药杂志(英文版),2022(09):400-409
A类:
TURCOVID,exclusions,Thorax
B类:
predictors,long,cohort,Turkish,Thoracic,Society,multicenter,registry,One,year,follow,up,results,Objective,To,effects,determine,risk,factors,TTS,Methods,Thirteen,centers,participated,patients,were,enrolled,after,study,was,designed,three,steps,Phone,questionnaire,retrospective,evaluation,medical,records,face,visit,Results,In,first,hospitalized,had,history,pneumonia,diagnosis,total,reported,clinical,symptoms,Dyspnea,fatigue,weakness,most,prevalent,incidence,increased,by,fold,presence,chronic,obstructive,pulmonary,disease,initial,dyspnea,persists,early,post,treatment,period,emergency,service,admission,analysis,revealed,that,chest,rays,not,significantly,improved,while,computed,tomography,scan,detected,fibrosis,admitted,least,persisted,common,psychiatric,Conclusions,last,extended,lengths,severity,well,comorbidities,might,contribute,Long,issues,should,be,regularly,evaluated
AB值:
0.477769
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