典型文献
Atypical manifestations of acute coronary syndrome-throat discomfort:a multi-center observational study
文献摘要：
To present the clinical characteristics and the misdiagnosis rate of acute coronary syndrome manifested primarily as throat discomfort,we conducted a multicentric and retrospective study in the cardiology and otorhinolaryngology departments.Records of patients with primary complaint of throat discomfort,absence of chest pain at onset,and an ultimate diagnosis of acute coronary syndrome,as well as patients with pharyngitis(as controls)were collected from May 2015 to April 2016.The patients'main manifestations were compared.Logistic regression results showed that chest tightness,dyspnea,perspiring,and exertional throat symptoms were significantly associated with acute coronary syndrome,with odds ratios of 8.3(95％CI 2.2-31.5),10.9(95％CI 1.8-66.9),25.4(95％CI 3.6-179.9),and 81.2(95％CI 13.0-506.7).A total of 25(56.82％)out of 44 acute coronary syndrome patients,who were first admitted to the otorhinolaryngology department,were misdiagnosed,with a 12％(3/25)mortality rate.Throat discomfort can be the principal manifestation of acute coronary syndrome.Such patients exhibit high misdiagnosis and mortality rates.Exertional throat symptoms,chest tightness,perspiring,and dyspnea were important indicators of acute coronary syndrome in patients whose main complaint was throat discomfort.The awareness of this condition will result in prompt diagnosis and reduce morbidity and mortality.
文献关键词：
中图分类号：
作者姓名：
Yanqing Fang;Xiaoting Cheng;Wenhui Peng;Xueying Chen;Chunping Tang;Qiusheng Huang;Sihai Wu;Yibo Huang;Fanglu Chi;Matthew R.Naunheim;Huawei Li;Bing Chen;Yilai Shu
作者机构：
ENT Institute and Department of Otorhinolaryngology,Eye&ENT Hospital,State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200031,China;Institutes of Biomedical Sciences,Fudan University,Shanghai 200031,China;NHC Key Laboratory of Hearing Medicine,Fudan University,Shanghai 200031,China;Department of Cardiology,Shanghai Tenth People,s Hospital,School of Medicine,Tongji University,Shanghai 200072,China;Department of Cardiology,Zhongshan Hospital,Fudan University,Shanghai Institute of Cardiovascular Diseases,National Clinical Research Centerfor Interventional Medicine,Shanghai 200032,China;Department of Cardiology,The First Affiliated Hospital,Nanjing Medical University,Nanjing 210029,China;Department of Otolaryngology,Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China;Department of Otorhinolarynogology,The Second Peopless Hospital of Wuxi,Nanjing Medical University,Wuxi 214002,China;Department of Otolaryngology-Head and Neck Surgery,Massachusetts Eye and Ear Infirmary,Harvard Medical School,Boston,MA 02114,USA
文献出处：
引用格式：
[1]Yanqing Fang;Xiaoting Cheng;Wenhui Peng;Xueying Chen;Chunping Tang;Qiusheng Huang;Sihai Wu;Yibo Huang;Fanglu Chi;Matthew R.Naunheim;Huawei Li;Bing Chen;Yilai Shu-.Atypical manifestations of acute coronary syndrome-throat discomfort:a multi-center observational study)[J].医学前沿,2022(04):651-658
A类：
otorhinolaryngology,perspiring,Throat,Exertional
B类：
Atypical,manifestations,acute,coronary,syndrome,throat,discomfort,center,observational,study,To,present,clinical,characteristics,misdiagnosis,manifested,primarily,conducted,multicentric,retrospective,cardiology,departments,Records,patients,primary,complaint,absence,chest,pain,onset,ultimate,well,pharyngitis,controls,were,collected,from,May,April,main,compared,regression,results,showed,that,tightness,dyspnea,exertional,symptoms,significantly,associated,odds,ratios,total,out,first,admitted,misdiagnosed,mortality,be,principal,Such,exhibit,high,rates,important,indicators,whose,was,awareness,this,condition,will,prompt,reduce,morbidity
AB值：
0.457736
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