Background:Despite remarkable advances in surgical techniques and perioperative management,left hep-atic trisectionectomy(LHT)remains a challenging procedure with a somewhat high postoperative mor-bidity rate compared with less-extensive resections.This study aimed to analyze the short-and long-term outcomes of LHT and identify factors associated with the postoperative morbidity of this technically de-manding surgical procedure.Methods:The medical records of 53 patients who underwent LHT between June 2005 and October 2019 at a single institution were retrospectively reviewed.The independent prognostic factor of postoperative morbidity was analyzed using the logistic regression model.Results:Hepatocellular carcinoma was the most common indication for surgery(n=21),followed by hilar cholangiocarcinoma(n=14),intrahepatic cholangiocarcinoma(n=10),and other pathologies(in-cluding colorectal liver metastasis,hepatolithiasis,gallbladder cancer,living donor,hemangioma,and mul-tilocular biliary cyst;n=8).The rates of postoperative morbidities of Clavien-Dindo grade 3 or higher and 90-day mortality were 39.6％and 1.9％,respectively.The 1-,3-,and 5-year overall survival rates were 81.1％,61.4％,and 44.6％,respectively.Multivariate analysis revealed that preoperative jaundice[hazard ratio(HR)=6.15,95％confidence interval(CI):1.57-24.17,P=0.009]and operative time＞420 min(HR=4.66,95％CI:1.27-17.17,P=0.021)were independent predictors of postoperative morbidity.Conclusions:The in-hospital mortality of LHT surgery can be minimalized by a reliable preoperative eval-uation of liver function and selection of the dominant anatomic features of right posterior sector,active and appropriate preoperative management for obstructive cholangitis and compensatory hypertrophy of the future remnant posterior sector,and the experience of the surgeon.

Young-In Yoon;Sung-Gyu Lee;Deok-Bog Moon;Shin Hwang;Ki-Hun Kim;Hui-Ju Kim;Ki-Hoon Choi

Division of Hepatobiliary Surgery and Liver Transplantation,Department of Surgery,Asan Medical Center,University of Ulsan College of Medicine,388-1 Poongnap-dong,Songpa-gu,Seoul 138-736,Korea;Department of Surgery,Gold Coast University Hospital,Southport,QLD 4215,Australia

国际肝胆胰疾病杂志(英文版)

[1]Young-In Yoon;Sung-Gyu Lee;Deok-Bog Moon;Shin Hwang;Ki-Hun Kim;Hui-Ju Kim;Ki-Hoon Choi-.Morbidity analysis of left hepatic trisectionectomy for hepatobiliary disease and live donor)[J].国际肝胆胰疾病杂志(英文版),2022(04):362-369

trisectionectomy,hepatolithiasis,tilocular,minimalized

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